1.
Chem Commun (Camb)
; 52(97): 13963-13966, 2016 Nov 29.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27844069
RESUMO
Nucleophilic 18F-fluorination of bromodifluoromethyl derivatives was performed using [18F]Bu4NF in the presence of DBU (1,8-diazabicyclo[5.4.0]undec-7-ene). This novel procedure provided a diverse set of [18F]trifluoroacetamides in good to excellent radiochemical conversions. A mechanism where DBU acts as organomediator in this transformation is proposed.