[Case of Gorlin syndrome]. / A propósito de un caso de "sindrome de Gorlin".

In this paper we report a Gorlin's syndrome in a patient, who was first diagnosed as a case of a large odontogenic keratocyst. Posterior analysis demonstrate the presence of other keratocyst in the maxilla and in the mandible, as well as lumbar scoliosis, lack and malformation of ribs, calcification of the brain sickle and folicles of 8 mm of diameter in the right ovary. The possible presence of nevoid basal cell carcinomas will be also considered.

Localisation of motoneurons supplying the extra-ocular muscles of the rat using horseradish peroxidase and fluorescent double labelling.

This paper describes a qualitative and quantitative investigation into the location of the motoneurons innervating the extra-ocular muscles of the rat. Injections of horseradish peroxidase, bisbenzimide, propidium iodide and DAPI-primuline were made either in one or simultaneously in two muscles. Unlike those of the cat, rabbit and monkey, the motoneurons which make up the oculomotor nucleus of the rat are not arranged in spatially separate subgroups belonging each to its corresponding extra-ocular muscle, but instead allow a high degree of superposition among the motor pools which they compose. The motoneurons innervating the lateral rectus and inferior oblique muscles are all homolateral; those of the medial and inferior rectus muscles are mainly homolateral with a few contralateral exceptions; and those of the superior rectus, levator palpebrae and superior oblique muscles are mainly contralateral with a small minority of homolateral exceptions. As well as from the main motor pools with which they are associated, the medial rectus, inferior rectus, superior rectus, levator palpebrae, superior oblique and lateral rectus muscles all receive innervation from motoneurons lying among the fibres of the fasciculus longitudinalis medialis. All these observations are supported by quantitative data.

Location and quantitative analysis of the motoneurons innervating the extraocular muscles of the guinea-pig, using horseradish peroxidase (HRP) and double or triple labelling with fluorescent substances.

The location of the motoneurons innervating the extraocular muscles of the guinea-pig was investigated using horseradish peroxidase (HRP) and the fluorescent substances fast blue, propidium iodide and nuclear yellow as retrograde tracers. The innervation of the inferior rectus, medial rectus and inferior oblique muscles is exclusively ipsilateral, and these neurons form three well-defined and mutually separate subnuclei in the oculomotor nucleus. The subgroup innervating the medial rectus lies exclusively along the medial face of the oculomotor nucleus, with no aberrant neurons in the medial longitudinal fasciculus, as have been found in other mammals. The superior rectus and levator palpebrae are innervated almost entirely by contralateral motoneurons located both in the oculomotor nucleus and in a variety of extranuclear positions (in the periaqueductal grey, among the fibres of medial longitudinal fasciculus and ventral to this bundle). There is no anteroposterior separation between the oculomotor and trochlear nuclei, since superior rectus and levator palpebrae neurons are found flanking the latter laterally all along its anterior half. In the caudal two-thirds of the oculomotor nucleus the motoneurons innervating the superior rectus and levator palpebrae are partially intermingled with those corresponding to the ipsilaterally-innervated muscles, particularly those of the inferior rectus.