[Regression of a choroidal metastasis from prostate adenocarcinoma after hormonal therapy]. / Regresión de una metástasis coroidea de adenocarcinoma de próstata con tratamiento hormonal.

CASE REPORT: We report a case of a patient diagnosed with prostatic adenocarcinoma with multiple bone metastases and a choroidal metastasis in his left eye. Hormonal therapy with an anti-androgen and a LH-RH agonist was followed by regression of the choroidal mass over a period of 2 months. No metastatic recurrence has been demonstrated after a follow-up period of 14 months. DISCUSSION: Complete resolution of choroidal metastases of prostatic adenocarcinoma with hormonal therapy is exceptional, but the effect of this treatment on such metastases should be observed before recommending radiation therapy.

Regresión de una metástasis coroidea de adenocarcinoma de próstata con tratamiento hormonal / Regression of a choroidal metastasis from prostate adenocarcinoma after hormonal therapy

Caso clínico: Paciente diagnosticado de adenocarcinoma de próstata con múltiples metástasis óseas, que también presentaba una gran metástasis coroidea en su ojo izquierdo. El tratamiento hormonal, mediante la asociación de un antiandrógeno y un análogo de LH-RH, obtuvo en 2 meses una rápida regresión de la metástasis, regresión que se mantiene a los 14 meses de seguimiento. Discusión: La desaparición de las metástasis coroideas en el adenocarcinoma de próstata con la terapia hormonal resulta excepcional aunque su efecto podría probarse antes de pautar la radioterapia como tratamiento electivo

Case report: We report a case of a patient diagnosed with prostatic adenocarcinoma with multiple bone metastases and a choroidal metastasis in his left eye. Hormonal therapy with an anti-androgen and a LH-RH agonist was followed by regression of the choroidal mass over a period of 2 months. No metastatic recurrence has been demonstrated after a follow-up period of 14 months. Discussion: Complete resolution of choroidal metastases of prostatic adenocarcinoma with hormonal therapy is exceptional, but the effect of this treatment on such metastases should be observed before recommending radiation therapy

[Fibroepithelial polyp of the urethra in an adult]. / Pólipo fibroepitelial de uretra en un adulto.

We present the case of a fibroepithelial polyp of the prostatic urethra in a forty-five year old patient. This type of polyp is rare in the adult. The principal symptoms which the patient presented were haematuria and an intermittent reduction in micturitional flow. Endoscopic images of the tumour are shown and certain details of its histology; this is a polypoid lesion of loose connective tissue covered by typical urothelium, with occasional fascicles of smooth muscle, no prostatic-type glandular structures and no appreciable inflammatory component.

Pólipo fibroepitelial de uretra en un adulto / Fibroepithelial urethral polyp in an adult

Presentamos el caso de un pólipo fibroepitelial de uretra prostática en un paciente de cuarenta y cinco años. Este tipo de pólipos son poco frecuentes en el adulto. Los síntomas principales que manifestaba el paciente eran hematuria y disminución ocasional del chorro miccional. Mostramos las imágenes endoscópicas del tumor, así como detalles de su histología que corresponde a una lesión polipoide con un revestimiento urotelial típico sobre tejido conectivo laxo, con algún fascículo de músculo liso sin estructuras glanduliformes de tipo prostático ni componente inflamatorio apreciable (AU)

[Non-functional renal paraganglioma associated with carotid paraganglioma and appendicular mucocele]. / Paraganglioma renal no funcionante asociado con un paraganglioma carotídeo y un mucocele apendicular.

OBJECTIVE: A case of nonfunctional renal paraganglioma associated with appendicular mucocele and metachronic carotid paraganglioma is presented. METHODS/RESULTS: A 68-year-old patient consulted for abdominal pain. Patient evaluation with US, CT and opague enema showed an elongated mass that compromised the cecum and a solid mass in the right kidney. The patient underwent appendectomy and radical right nephrectomy. The anatomopathological findings showed an appendicular mucocele and renal paraganglioma. The postoperative hormone analyses were normal. A carotid paraganglioma was removed 8 months later. CONCLUSIONS: Renal tumors arising from neural crest cells are uncommon. To our knowledge, this is the third case of nonfunctional renal paraganglioma reported in the literature. The associated appendicular mucocele was an incidental finding.

[Innervation of the human adrenal gland]. / Inervación de la glándula suprarrenal humana.

OBJECTIVE: To study the innervation of the human adrenal gland by immunohistochemical techniques using monoclonal antibodies against the 200-kDa phosphorylated neurofilament and S-100 protein, specific markers of the axons and Schwann cells, respectively. METHODS: 24 specimens of normal adrenal gland from patients that had undergone radical nephrectomy for a renal tumor were analyzed. The tissue was embedded in paraffin and prepared for analysis by immunohistochemical techniques with the indirect peroxidase method using primary monoclonal antibodies against the 200-kDA phosphorylated neurofilament and protein S-100. RESULTS: The nerves localized in the adrenal gland form a subcapsular plexus where branches arise that extend to the medulla and come into contact with the enterochromaffin cells and medullary neurons. The adrenal neurons are restricted to the medulla; they are dispersed or form ganglia. The satellite cells of the medullary ganglia and the sustentacular cells were positive for S-100. CONCLUSIONS: Most of the nerve fibers penetrate into the human adrenal gland, extending directly to the medulla apparently without coming into contact with the cells of the adrenal cortex and form similar connections to the synaptics with the chromaffin cells and the medullary neurons. The microganglia of the human adrenal gland are dispersed and comprised of few neurons.

[Adrenal tuberculosis. Diagnosis using polymerase chain reaction]. / Tuberculosis suprarrenal. Diagnóstico mediante la reacción en cadena de la polimerasa.

OBJECTIVE: To present a case of a patient suffering from adrenocortical insufficiency (Addison's disease) and to demonstrate the utility of the polymerase chain reaction (PCR) in the diagnosis of adrenal cortex tuberculosis. METHODS/RESULTS: Herein we describe a patient with Addison's disease who had developed pulmonary tuberculosis a few years earlier. CT and PCR test were utilized in making the diagnosis. CONCLUSION: Although adrenocortical tuberculosis is uncommon today, it must be considered when evaluating adrenocortical insufficiency, especially if the patient has or has had tuberculosis. Although Mycobacterium tuberculosis might not be demonstrated by bacteriologic techniques, PCR can be useful in making the etiological diagnosis.

[Blind ureter ending in ejaculatory duct. Report of a case]. / Ureter ciego desembocando en conducto eyaculador. A propósito de un caso.

OBJECTIVES: Herein we describe a case of an extremely uncommon malformation of the genitourinary system in a patient who had consulted for epididymitis. METHODS: Patient evaluation included radiological examination, IVP, US, CT and DVG The latter method was essential in the diagnosis of the malformation. RESULTS: The findings indicated left renal agenesis with blind left ureter opening to the ipsilateral ejaculatory duct, with severe deformity of the left seminal vesicle and ejaculatory duct. CONCLUSIONS: Since the patient has no important symptoms at the present time, contrary to the widely accepted approach, surgery has not been performed due to the risk of causing an iatrogenic lesion.

[Pure prostatic leiomyoma]. / Leiomioma prostático puro.

We report a case of pure leiomyoma of the prostate, an uncommon benign tumor with a leiomyomatous component distinct from benign prostatic hyperplasia. The literature is reviewed and several considerations are put forward relative to the etiopathogenesis, clinical and anatomopathological features, differential diagnosis and prognosis of this tumor.

[Acquired cystic renal disease: a case of intracystic hemorrhage simulating renal tumor]. / Enfermedad quística renal adquirida: un caso de hemorragia intraquística simulando tumoración renal.

We report a case of intracystic hemorrhage in a patient with acquired cystic kidney disease, undergoing hemodialysis. A surgical procedure was performed owing to the discrepancy between the clinical and radiological findings. The histological analyses revealed no evidence of kidney tumours.

[Bladder amyloidosis]. / Amiloidosis vesical.

We present a case of Vesical Amyloidosis (V.A.) in a woman with Rheumatoid Arthritis. Clinical data, other locations and Histochemical findings are consistent with Secondary Amyloidosis. After T.U.R., she was treated with Dimethylsulfoxide (DMSO) and Colchicine. Her severe hematuria disappeared.

Granulomatous prostatitis.

Twenty cases of granulomatous prostatitis are presented. They were identified, histologically or cytologically, among 1,316 patients with prostatic pathology at the General Hospital of Asturias during a period of 3 years (Jan. 1984 to Dec. 1986). The etiology, histogenesis, clinical and morphological aspects, treatment and prognosis of the different types of granulomatous prostatitis, according to a classification by the authors, are discussed. The significance of the differentiation of granulomatous prostatitis from carcinoma is discussed. Fine-needle aspiration cytology (Franzen) is recommended as the diagnostic method of choice.