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1.
Niger J Clin Pract ; 27(5): 647-653, 2024 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-38842715

RESUMO

BACKGROUND: The occipital spur (OS) can be described as an abnormal elongation of the external occipital protuberance (EOP). The cephalic index (CI) refers to the ratio of width to length in any skull. AIM: The aim of the present study was to evaluate the frequency and types of OS. It also aimed to determine the mean CI and the distribution of skull types using cone beam computed tomography (CBCT). And to determine if there was a relationship between the cephalic index and the presence and types of OS. METHODS: CBCT scans from 523 patients were included in the study. OSs were classified as type 1 (flat), type 2 (crest), and type 3 (spine). Skull length and width were measured on axial sections and the CI was calculated. Based on the cephalic index (CI), skull types were classified as dolichocephalic (CI < 75), mesocephalic (75 < CI < 80), brachycephalic (80 < CI < 85), and hyperbrachycephalic (CI > 85). RESULTS: The most common cranial types in the study group were brachycephalic (44.7%), mesocephalic (28.3%), hyperbrachycephalic (21.2%), and dolichocephalic (5.7%). Regarding the presence of OS, 54.3% of the participants had no OS, 23.1% had flat type, 15.3% had crest type, and 7.2% had spin type OS. There was a statistically significant difference (P < 0.05) in the frequency of OS according to skull type. CONCLUSION: This study, the first to evaluate CI and OS using CBCT, concludes that brachycephaly is the most common cranial type. OS is more common in mesocephalic and dolichocephalic skulls, at older ages, and in males.


Assuntos
Cefalometria , Tomografia Computadorizada de Feixe Cônico , Osso Occipital , Humanos , Tomografia Computadorizada de Feixe Cônico/métodos , Masculino , Feminino , Osso Occipital/diagnóstico por imagem , Osso Occipital/anatomia & histologia , Adulto , Pessoa de Meia-Idade , Cefalometria/métodos , Adolescente , Adulto Jovem , Criança , Idoso , Pré-Escolar , Crânio/diagnóstico por imagem , Crânio/anatomia & histologia
2.
Farmakol Toksikol ; 38(5): 563-5, 1975.
Artigo em Russo | MEDLINE | ID: mdl-1102329

RESUMO

Comparative pharmacological and toxicological studies were carried out on animals covering the preparation d,1-oxyphedrine (myophedrine), put out in the GDR, as against the drug 1-oxyphedrine. The activity of both drugs showed no material difference. Clinical trials demonstrated good tolerance of the drug both by healthy persons and patients with its intravenous administration twice a day in amounts of 1 mg, or by mouth--3 times a day in amounts of 8--16 mg. In outpatients with anginal pains after sustained myocardial infarction and also in institutionally treated patients with myocardial infarction the activity of d,1-oxyphedrine proved to be not inferior to that of 1-oxyphedrine.


Assuntos
Oxifedrina/farmacologia , Propiofenonas/farmacologia , Adulto , Idoso , Assistência Ambulatorial , Animais , Pressão Sanguínea/efeitos dos fármacos , Ensaios Clínicos como Assunto , Cães , Relação Dose-Resposta a Droga , Feminino , Cobaias , Frequência Cardíaca/efeitos dos fármacos , Hospitalização , Humanos , Técnicas In Vitro , Dose Letal Mediana , Masculino , Camundongos , Pessoa de Meia-Idade , Infarto do Miocárdio/tratamento farmacológico , Oxifedrina/efeitos adversos , Ratos , Fatores de Tempo
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