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1.
Rheumatol Int ; 27(8): 723-7, 2007 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17225054

RESUMO

AIM: Vitamin D deficiency is one of the most important risk factors in the development of osteoporosis. Recently, vitamin D deficiency is more frequently encountered than expected in Mediterranean countries, which are sunny most of the time. Our country is one of these sunny countries and here, we investigated the effect of outfitting style on bone mineral density (BMD) and plasma vitamin D levels in women aged between 30-40 years. METHOD: Eighty women, aged between 30 and 40 years, were included in the study. They were divided into two groups, depending on their dress selection. Group-1 consisted of 40 cases with an open clothing style, while the 40 women in group-2, preferred the covered clothing style. Women were questioned in terms of the risk factors for osteoporosis. Levels of plasma 25(OH)2 vitamin D3 and parathormone (PTH) were tested along with routine blood analyses. BMD of Lumbar 1-4, femur neck, trochanter, and Ward's triangle were measured. RESULTS: In group-2, number of pregnancies and body mass index (BMI) was statistically significantly higher (p < 0.05). When the laboratory parameters were compared, in group-2, only levels of plasma 25 (OH)2 vitamin D3 was significantly lower than group-1 (p < 0.05). There was no significant difference among groups in terms of BMD. In group-2, there was a positive correlation between BMI and BMD at L1-4, hip, femur neck, and trochanter regions (p < 0.01, 0.01, 0.05, and 0.05, respectively). CONCLUSION: Traditional clothing style leads to vitamin D deficiency in women. In order to meet vitamin D need, the face, arm and leg regions of the body should be exposed to one minimal erythemal dose (MED; i.e., slight redness of the skin) of sunlight, at least two or three times a week. We believe that these cases should be more closely monitored for bone loss, especially during postmenopausal period, which is considered as a risky term in terms of osteoporosis development.


Assuntos
Densidade Óssea , Colecalciferol/sangue , Vestuário/efeitos adversos , Hormônio Paratireóideo/sangue , Deficiência de Vitamina D/etiologia , Adulto , Estudos de Coortes , Feminino , Humanos , Estações do Ano , Turquia , Raios Ultravioleta , Deficiência de Vitamina D/etnologia
2.
Rheumatol Int ; 27(7): 679-81, 2007 May.
Artigo em Inglês | MEDLINE | ID: mdl-17171347

RESUMO

Non-prescribed antacid drugs that contain magnesium and aluminum are widely used in the treatment of gastritis and peptic ulcer. One of the side effects of these antacid drugs is that they bind phosphate in the gut and result in its malabsorption. In this paper, a 42-year-old female patient who used magnesium hydroxide (Magnesie calcinee powder 100 g) to benefit from its laxative feature, and developed osteomalacia after losing 90 kg in 2 years will be presented by going through the related literature. She had widespread joint pain and could hardly walk without the help. Ca, P and vitamin D were at lower limit of normal, ALP, Mg and PTH were increased in her laboratory tests. There were stress fractures at the femur neck and at the upper part of the tibia in plane radiographies. The patient was hospitalized with the diagnosis of osteomalacia and she was treated successfully.


Assuntos
Antiácidos/efeitos adversos , Catárticos/efeitos adversos , Fraturas do Colo Femoral/etiologia , Hidróxido de Magnésio/efeitos adversos , Osteomalacia/induzido quimicamente , Adulto , Antiácidos/administração & dosagem , Catárticos/administração & dosagem , Feminino , Fraturas do Colo Femoral/diagnóstico por imagem , Humanos , Hidróxido de Magnésio/administração & dosagem , Osteomalacia/complicações , Osteomalacia/diagnóstico por imagem , Radiografia , Fraturas da Tíbia/diagnóstico por imagem , Fraturas da Tíbia/etiologia
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