[Circadian rhythms of mineral-excreting kidney function in healthy persons and their changes in ischemic heart disease]. / Okolosutochnye ritmy mineralvydelitel'noi funktsii pochek u zdorovykh lits i ikh izmeneniia pri ishemicheskoi bolezni serdtsa.

Seventy normal persons and 100 patients with coronary disease were examined for circadian rhythms of urine and minerals excretion. The data obtained demonstrate that normal persons were characterized by circadian rhythms of urine and minerals excretion with a definite confidence interval of mesor and amplitude fluctuations. Angina pectoris of effort was marked by infradian rhythms of mineral excreting renal function. Monotherapy with beta-blockers or calcium antagonists given in courses entailed the recovery of the circadian rhythms of mineral-excreting renal function. Parameters of the rhythms of urine and minerals excretion in patients with angina pectoris of effort and rest noticeably differed from those in patients with angina pectoris of effort. In 30.7 percent of the persons, the use of the mathematic methods did not reveal any significant rhythms. The circadian range was found to predominate among the significant rhythms. Antianginal treatment did not produce any appreciable changes.

[Types of disorders of the contractile function of the heart in acute myocardial infarct]. / O tipakh narusheniia sokratitel'noi funktsii serdtsa pri ostrom infarkte miokarda.

Acute myocardial infarction is characterized by reduced contractile activity of the heart, which is manifested by pathological shifts in the phase structure of the left ventricular systole and parameters of hemodynamics corresponding to the syndrome of hypodynamia. The severity of the hypodynamia syndrome depends on the volume of the affected myocardium. On the basis of the degree of pathological shifts in the phase and hemodynamic indices, the authors distinguished several types of impaired cardiac contractility. In the course of stage-by-stage treatment applied on the principles of early activation, mobilization, and rehabilitation of patients, the dynamics differs with the type of the contractility disorder. In type I positive dynamics is revealed beginning with stage I, in type II beginning with stage II of treatment; in type III negative dynamics is noted in the early periods of the disease and positive dynamics in stage III of treatment. The differentiation of these types becomes very important in appraising the tactics, the prognosis, and the outcome of the disease. Close correlative relations were revealed between the phase indices and the indices of hemodynamics which allow more objective appraisal of the state of cardiac contractility in the acute period of myocardial infarction.