Children of treated substance-abusing mothers: a 10-year prospective study.

This study examined children of substance-abusing mothers approximately 10 years after mothers' admission to drug abuse treatment, and identified maternal characteristics that may be risk factors for child behavior problems on the Child Behavior Checklist. Data were obtained from 396 mothers who were included in a sample consecutively admitted to 44 treatment programs in 13 California counties during 2000-2002. The Addiction Severity Index was administered at both intake and follow-up. Each mother reported on one child 6-17 years of age. All of the children had been exposed to drugs, either in utero or postnatally. At follow-up about 22% of the children demonstrated borderline or clinical range problem behaviors. Child behavior problems were related significantly to the mothers' ethnicity (lower among Hispanics relative to white), and problem severity in family/social relationship and mental health, marginally related to her prior medical/health problem, and not related to severity of alcohol, drug, legal and employment problems. Assisting mothers to address their family/social relationship and psychological problems may have an added value to prevent or reduce behavioral problems of their children.

A preliminary neuroimaging study of preschool children with ADHD.

Attention-deficit/hyperactivity disorder (ADHD) is a developmental disorder that, by current definition, has onset prior to age 7 years. MRI studies have provided some insight into brain differences associated with ADHD, but thus far have almost exclusively focused on children ages 7 years and older. To better understand the neurobiological development of ADHD, cortical and subcortical brain development should be systematically examined in younger children presenting with symptoms of the disorder. High-resolution anatomical (MPRAGE) images, acquired on a 3.0T scanner, were analyzed in a total of 26 preschoolers, ages 4-5 years (13 with ADHD, 13 controls, matched on age and sex). The ADHD sample was diagnosed using DSM-IV criteria, and screened for language disorders. Cortical regions were delineated and measured using automated methods in Freesurfer; basal ganglia structures were manually delineated. Children with ADHD showed significantly reduced caudate volumes bilaterally; in contrast there were no significant group differences in cortical volume or thickness in this age range. After controlling for age and total cerebral volume, left caudate volume was a significant predictor of hyperactive/impulsive, but not inattentive symptom severity. Anomalous basal ganglia, particularly caudate, development appears to play an important role among children presenting with early onset symptoms of ADHD.

The male experience of pubertal change.

Adolescent boys' psychological experience of the first ejaculation was examined with regard to emotional reactions to the event, feelings of preparedness prior to the event, informational sources, and extent of peer discussions following the event. Thirteen boys who ranged in age from 13 1/2 to 15 1/2 years were interviewed. Eleven of the boys had experienced an ejaculation; 55% felt they were well informed prior to the first ejaculation. However, only three had had ejaculation explained to them by another person, in all cases an adult male. The primary information source was reading material aquired from friends. The majority of the boys reported experiencing strong positive feelings at spermarche, and few had strong negative feelings. No one was upset or ashamed, and only two were very scared. The only boys who had discussed the experience were the three who received their initial information from adult males. No one had discussed the experience with peers. Differences and similarities in boys' experience of ejaculation and girls' experience of menarche are discussed.