[Calculation of the capacity of a roller pump]. / Raschet proizvoditel'nosti rolikovogo nasosa.

The capacity (G) of the roller pump was calculated for pipes of different rigidity. It was shown that the value G related to the viscosity of the liquid will be determined either by the roller revolution speed or by the pipe elasticity characteristics. Methods of calculation for choosing the optimum pipe type are described.

[Effect of diet on the formation of chyme and the rate of absorption of nutrients during active digestion]. / Vliianie ratsiona na formirovanie khimusa i temp vsasyvaniia pitatel'nykh veshchestv v khode aktivnogo pishchevareniia.

In dogs with multiple fistulae the rate of absorption of nutrients from enteral lumen using different nutrient mixtures, revealed that the composition of chyme at the entrance into small intestine is homeostased within a certain range of values differing from the diet. A considerable increase of some nutrient in the diet leads to an increase of its content in the chyme and to considerable acceleration of absorption from the gastroduodenal part.

[Chyme homeostasis in the gastroduodenal portion of the digestive tract under different nutritional diets]. / Gomeostatirovanie khimusa v gastroduodenal'nom otdele pishchevaritel'nogo trakta pri razlichnykh ratsionakh pitaniia.

The concentration of chyme ingredients and volumetric velocity of the chyme transfer from the duodenum to the jejunum were investigated in experiments on normal preoperated dogs with fistulas implanted into the stomach, duodenum and jejunum after feeding different diets throughout the entire process of active digestion. It has been established that as a result of exchange between the medium filling the gastroduodenal part of the alimentary tract and blood, an enteral medium is formed in the duodenum, with the composition of this medium being relatively constant as regards the concentration and constituent ingredients. It has been also shown that the direction of the balanced flows of the nutrients depends on their concentration in the diet and that both immediate exchange of substances between the enteral and internal media, which is effected according to the concentration gradient, and regulatory alterations in the secretion are involved in homeostasis of the enteral medium.

[Effect of homeostasis of chyme composition on absorption of its components in the small intestine during natural digestion]. / Vliianie gomeostatirovaniia sostava khimusa na vsasyvanie ego komponentov v tonkoi kishke v usloviiakh estestvennogo pishchevareniia.

In dogs, even after essential changes of food ingredients, chyme concentration indices, being formed in duodenum, are steadily kept over a comparatively small range of values in the aftermath of intensive exchange between blood and media filling the lumen of gastroduodenal area. The direction of the balance flow for each substance depends both on the substance initial concentration and the ingredients ratio of food. The homeostating of enteral medium seems to assure the relative stability of the substances balance flow filling up internal medium of the organism.

[Detoxification of portal system blood in the combined treatment of peroral poisonings]. / Detoksikatsiia krovi portal'noi sistemy v kompleksnom lechenii peroral'nykh otravlenii.

A combined method for body detoxification including extracorporeal purification of the blood outflowing from the intestine with sorbents and emergency evacuation of the small intestine contents by means of a tube was employed in acute experiments on dogs after oral administration of the lethal doses of veronal. Tht use of the method interferes with the poison supply from the gastrointestinal tract to the systemic blood flow, thereby leading to acceleration of body detoxification.

[Unit complex for electrophysiological research and computer information input]. / Apparaturnyi kompleks dlia élektrofiziologicheskikh issledovanii i vvoda informatsii v EVM.

A multichannel digital-to-analog system for polyfunctional physiologic studies requiring computer-ailed laboratory data processing is developed. The system performs an acquisition, conversion and recording of functional parameters. Built in the system additional units make it possible along with recording and digitizing the input information to record data on a tape recorder with further loading to a computer. Described in the paper is the unit complex that permits simultaneous recording the electric, locomotive and evacuant intestinal activity under experimental conditions and subsequent computer-aided data processing.

[Enzymes in the mucosal layer of the small intestine]. / Fermenty sloia slizi tonkoi kishki.

It has been demonstrated by the methods of histochemical and biochemical examination of the activity of the enzymes that the mucus layer covering the small intestinal wall contains active enzymes (alkaline phosphatase, leucin aminopeptidase IV, saccharase, lactase) and pancreatic enzymes (alpha-amylase and trypsin). Emphasis is laid on the enrichment of the mucus layer with pancreatic enzymes as compared with small intestinal juice. A hypothesis has been advanced according to which the mucus layer undergoes degradation of polymeric and oligomeric substrates, which plays a physiological part in the digestion of nutritive substances and protection of the internal medium against immunoactive biopolymers. The digestion occurring in the mucus layer is proposed to be called mucus digestion.

[Electron microscopic study of 3H-leucine transport between the internal body environment and the enteral environment]. / Elektronno-mikroskopicheskoe issledovanie transporta 3H-leitsina mezhdu vnutrennei sredoi organizma i énteral'noi sredoi.

Using electron microscopic autoradiography, a space-time characteristics of 3H-leucine transport, from the enteral to the inner environment, and from blood plasma to the enteral environment, has been given. Some gradient of intracellular leucin accumulation is determined, from the tip cells of a villus to epithelocytes of the basal membrane. Amino acid transport from blood plasma to the lumen of the intestine is accomplished mainly via the cytoplasm and intercellular space of epithelocytes of the villus basement. It is proposed that amino acid transport through membranes of microvilli and through basal-lateral membranes of cells being on various levels along the villus may start at different amino acid concentrations which may be, presumably, to different concentration and different conjugation of enzyme-transport complexes in these membranes.