Resultados de la esofagectomía por cáncer tras la creación de un Comité de Tumores Esofagogástricos / Surgical outcomes of esophageal cancer resection since the development of an oesophagogastric tumour board

Introducción El tratamiento del cáncer de esófago con pretensión curativa requiere un planteamiento multidisciplinar. La terapia neoadyuvante, la radicalidad de la resección y la extensión de la linfadenectomía pueden incrementar la morbimortalidad postoperatoria. El objetivo de este estudio es analizar los resultados del tratamiento quirúrgico del cáncer de esófago desde la creación del Comité de Tumores Esofagogástricos. Método sEstudio retrospectivo (de enero de 2005 a marzo de 2012) de todos los pacientes con cáncer de esófago o de la unión esofagogástrica a los que se les realizó una esofagectomía. Se analizaron el tipo de resección, las complicaciones postoperatorias, la mortalidad y la supervivencia. Resultados: A 100 pacientes de un total de 392 diagnosticados se les realizó una esofagectomía. En 74 casos se administró tratamiento neoadyuvante. Se realizaron 82 esofagectomías transtorácicas en 2 o 3 campos, 10 esofagectomías transhiatales y 8 coloplastias. En 98 pacientes la resección fue R0. Se diagnosticaron 9 dehiscencias anastomóticas intratorácicas y 6 cervicales. La morbilidad global fue del 42% y la mortalidad hospitalaria y a los 90 días fue del 2%. La mediana de la estancia hospitalaria fue de 16 días. La supervivencia actuarial al año es del 82% y a los 5 años, del 56%.ConclusionesEl tratamiento quirúrgico con intención curativa de la neoplasia de esófago solo es posible en una cuarta parte de los pacientes diagnosticados. La elevada morbilidad se debe, sobre todo, a complicaciones torácicas (AU)

Introduction Treatment of oesophageal cancer with curative intent requires a multidisciplinary approach. Neoadjuvant therapy, the radicality of resection and extension of lymphadenectomy have been associated with increased operative morbidity and mortality. The aim of this study was to assess the results of surgical treatment of oesophageal cancer since the presence of an interdisciplinary esophagogastric tumour board. Methods Patients with cancer of the oesophagus and oesophagogastric junction who underwent oesophagectomy between January 2005 and March 2012 were included in this retrospective study. Data concerning type of resection, postoperative complications, mortality and survival were analysed. Results Of the 392 patients with a diagnosis of oesophageal cancer over the study period, 100 underwent oesophagectomy. Seventy-four patients received neoadjuvant treatment. Eighty-two patients underwent transthoracic resection while a transhiatal was used in 10 patients. Colon interposition was required in 8 cases. An R0 resection was achieved in 98 patients. Anastomotic leaks developed in 15 patients, 9 were intrathoracic and 6 were cervical. Postoperative morbidity occurred in 42% of patients, and intra-hospital and 90-day mortality was 2%. Median length of hospital stay was 16 days. The respective actuarial survival at 1 and 5 years were 82% and 56%.ConclusionsSurgical treatment with curative intention for oesophageal cancer is only possible in a quarter of patients diagnosed. The high morbidity rate was mainly due to intrathoracic complications (AU)

[Surgical outcomes of esophageal cancer resection since the development of an Oesophagogastric Tumour Board]. / Resultados de la esofagectomía por cáncer tras la creación de un Comité de Tumores Esofagogástricos.

INTRODUCTION: Treatment of oesophageal cancer with curative intent requires a multidisciplinary approach. Neoadjuvant therapy, the radicality of resection and extension of lymphadenectomy have been associated with increased operative morbidity and mortality. The aim of this study was to assess the results of surgical treatment of oesophageal cancer since the presence of an interdisciplinary esophagogastric tumour board. METHODS: Patients with cancer of the oesophagus and oesophagogastric junction who underwent oesophagectomy between January 2005 and March 2012 were included in this retrospective study. Data concerning type of resection, postoperative complications, mortality and survival were analysed. RESULTS: Of the 392 patients with a diagnosis of oesophageal cancer over the study period, 100 underwent oesophagectomy. Seventy-four patients received neoadjuvant treatment. Eighty-two patients underwent transthoracic resection while a transhiatal was used in 10 patients. Colon interposition was required in 8 cases. An R0 resection was achieved in 98 patients. Anastomotic leaks developed in 15 patients, 9 were intrathoracic and 6 were cervical. Postoperative morbidity occurred in 42% of patients, and intra-hospital and 90-day mortality was 2%. Median length of hospital stay was 16 days. The respective actuarial survival at 1 and 5 years were 82% and 56%. CONCLUSIONS: Surgical treatment with curative intention for oesophageal cancer is only possible in a quarter of patients diagnosed. The high morbidity rate was mainly due to intrathoracic complications.