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1.
Sci Rep ; 14(1): 9839, 2024 Apr 29.
Artigo em Inglês | MEDLINE | ID: mdl-38684724

RESUMO

This study explores the dynamical rotary motion of a charged axisymmetric spinning rigid body (RB) under the effect of a gyrostatic moment (GM). The influence of transverse and invariable body fixed torques (IBFTs), and an electromagnetic force field, is also considered. Euler's equations of motion (EOM) are utilized to derive the regulating system of motion for the problem in a suitable formulation. Due to the lack of torque exerted along the spin axis and the nearly symmetrical nature of the RB, the spin rate is nearly unchanged. Assuming slight angular deviations of the spin axis relative to a fixed direction in space, it is possible to derive approximate analytical solutions (AS) in closed form for the attitude, translational, and rotational movements. These concise solutions that are expressed in complex form are highly effective in analyzing the maneuvers performed by spinning RBs. The study focuses on deriving the AS for various variables including angular velocities, Euler's angles, angular momentum, transverse displacements, transverse velocities, axial displacement, and axial velocity. The graphical simulation of the subsequently obtained solutions is presented to show their precision. Furthermore, the positive impacts that alterations in the body's parameters have on the motion's behavior are presented graphically. The corresponding phase plane curves, highlighting the influence of different values in relation to the electromagnetic force field, the GM, and the IBFTs are drawn to analyze the stability of the body's motion. This study has a significant role in various scientific and engineering disciplines. Its importance lies in its ability to optimize mechanical systems, explain celestial motion, and enhance spacecraft performance.

2.
Sci Rep ; 14(1): 5390, 2024 Mar 05.
Artigo em Inglês | MEDLINE | ID: mdl-38443505

RESUMO

This paper aims to explore the rotatory spatial motion of an asymmetric rigid body (RB) under constant body-fixed torques and a nonzero first component gyrostatic moment vector (GM). Euler's equations of motion are used to derive a set of dimensionless equations of motion, which are then proposed for the stability analysis of equilibrium points. Specifically, this study develops 3D phase space trajectories for three distinct scenarios; two of them are applied constant torques that are directed on the minor and major axes, while the third one is the action of applied constant torque on the body's middle axis. Novel analytical and simulation results for both scenarios of constant torque applied along the minor and middle axes are provided in the context of separatrix surfaces, equilibrium manifolds, periodic or non-periodic solutions, and periodic solutions' extreme. Concerning the scenario of a directed torque on the major axis, a numerical solution for the problem is presented in addition to a simulation of the graphed results for the angular velocities' trajectories in various regions. Moreover, the influence of GM is examined for each case and a full modeling for the body's stability has been present. The exceptional impact of these results is evident in the development and assessment of systems involving asymmetric RBs, such as satellites and spacecraft. It may serve as a motivating factor to explore different angles within the GM in similar cases, thereby influencing various industries, including engineering and astrophysics applications.

3.
Sci Rep ; 13(1): 20288, 2023 Nov 20.
Artigo em Inglês | MEDLINE | ID: mdl-37985730

RESUMO

Due to the growing concentration in the field of the nonlinear oscillators (NOSs), the present study aims to use the general He's frequency formula (HFF) to examine the analytical representations for particular kinds of strong NOSs. Three real-world examples are demonstrated by a variety of engineering and scientific disciplines. The new approach is evidently simple and requires less computation than the other perturbation techniques used in this field. The new methodology that is termed as the non-perturbative methodology (NPM) refers to this innovatory strategy, which merely transforms the nonlinear ordinary differential equation (ODE) into a linear one. The method yields a new frequency that is equivalent to the linear ODE as well as a new damping term that may be produced. A thorough explanation of the NPM is offered for the reader's convenience. A numerical comparison utilizing the Mathematical Software (MS) is used to verify the theoretical results. The precise numeric and theoretical solutions exhibited excellent consistency. As is commonly recognized, when the restoration forces are in effect, all traditional perturbation procedures employ Taylor expansion to expand these forces and then reduce the complexity of the specified problem. This susceptibility no longer exists in the presence of the non-perturbative solution (NPS). Additionally, with the NPM, which was not achievable with older conventional approaches, one can scrutinize examining the problem's stability. The NPS is therefore a more reliable source when examining approximations of solutions for severe NOSs. In fact, the above two reasons create the novelty of the present approach. The NPS is also readily transferable for additional nonlinear issues, making it a useful tool in the fields of applied science and engineering, especially in the topic of the dynamical systems.

4.
Andrologia ; 48(9): 914-922, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26771175

RESUMO

Fluvoxamine is recommended as first-line treatment for a number of obsessive-compulsive disorders, anxiety disorders, social phobia, and post-traumatic stress disorder and panic disorder. The adverse effects of prolonged oral administration of fluvoxamine on haematology, biochemical parameters and fertility in male rats were evaluated in this study. Sixty adult male rats were allocated into 5 equal groups and orally treated with fluvoxamine 9 mg kg-1 b.wt. (low therapeutic dose, LTD) and 27 mg kg-1 b.wt. (high therapeutic dose, HTD), while the control rats received 0.5 ml distilled water for a period of 8 weeks. The 4th and 5th groups were gavaged with LTD and HTD of fluvoxamine for 8 weeks and then left untreated for another 8 weeks (recovery groups). HTD of fluvoxamine induced leukocytosis, lymphocytosis and monocytosis. LTD and HTD of fluvoxamine evoked hepatic, renal and cardiac dysfunction. Moreover, fluvoxamine treatment might lead to the risk of male infertility, which is indicated by its deleterious impacts on spermiogram and steroidogenesis hormones. They also induced oxidative stress, apoptosis in testicular tissue. Fortunately, the previous alterations were mostly reversed during the recovery period.


Assuntos
Fertilidade/efeitos dos fármacos , Fluvoxamina/efeitos adversos , Inibidores Seletivos de Recaptação de Serotonina/efeitos adversos , Administração Oral , Alanina Transaminase/sangue , Animais , Análise Química do Sangue , Fragmentação do DNA , Relação Dose-Resposta a Droga , Fluvoxamina/administração & dosagem , Hormônios Esteroides Gonadais/sangue , Leucocitose/induzido quimicamente , Masculino , Estresse Oxidativo/efeitos dos fármacos , Ratos , Inibidores Seletivos de Recaptação de Serotonina/administração & dosagem , Espermatozoides/efeitos dos fármacos , Testículo/efeitos dos fármacos , Testículo/metabolismo , Testículo/patologia
5.
J Adv Res ; 4(3): 275-8, 2013 May.
Artigo em Inglês | MEDLINE | ID: mdl-25685428

RESUMO

A solar activity precursor technique of spotless event has been currently used to predict the strengths and the times of rise of the 11-year coming cycles. This simple statistical method has been previously applied to predict the maximum amplitudes and the times of rises of cycles 22 and 23. The results obtained are successful for both cycles. A developed version of the suggested method was previously used to make an early forecast of the characteristic parameters of the cycle 24. In this work the preliminarily predicted parameters of the cycle 24 are checked using observed values of the spotless events. In addition, the developed method is also applied to forecast the maximum amplitude and time of rise of the 25th solar cycle. The maximum Wolf number and time of rise of the latter cycle are found to be 118.2 and 4.0 years respectively.

6.
J Egypt Soc Parasitol ; 19(1): 149-56, 1989 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-2708851

RESUMO

The course of Trichinella spiralis infection was studied in Alloxan induced diabetes in mice. The number of Trichinella larvae in muscles of infected animals was estimated by digestion of whole carcases and compared with control non diabetic group. Histopathological study of infected muscles was also done. It was found that diabetic mice developed very heavy muscle parasitism and their larval count was high compared with non diabetic animals. Besides, there was heavy inflammatory cellular reaction around poorly encapsulated larvae. Mortality rate was 100% by day 45 in diabetic mice while control animals survived during the period of observation which was 3 months. These data indicated that hyperglycaemia significantly increased parasitisaemia and mortality in mice infected with T. spiralis.


Assuntos
Diabetes Mellitus Experimental/complicações , Triquinelose/complicações , Aloxano , Animais , Larva/crescimento & desenvolvimento , Camundongos , Músculos/parasitologia , Músculos/patologia , Trichinella/crescimento & desenvolvimento
7.
J Egypt Soc Parasitol ; 18(2): 723-4, 1988 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-3418170
8.
Med Trop (Mars) ; 44(4): 339-49, 1984.
Artigo em Francês | MEDLINE | ID: mdl-6394948

RESUMO

The authors report some failures of chemoprophylaxis and curative treatment of Plasmodium falciparum and Plasmodium vivax malaria. These infections were contracted in the area of the cambodian-thaï border by 8 Europeans treated by various regimens and 34 Cambodians treated by quinine. In the latter group, the quinine failure rate in Plasmodium falciparum infections was about 47% (RII or RIII?) and 17,5% in Plasmodium vivax. Total cure of vivax malaria with usual doses of Primaquine among the Europeans, failed in 3 out of the 6 treated patients. Morphological particularities (abnormal pigment, lack of Schüffner dots) were noticed in these Primaquine resistant vivax strains. A possible relation is considered between Primaquine resistance and these morphological particularities.


Assuntos
Antimaláricos/farmacologia , Malária/tratamento farmacológico , Plasmodium falciparum/efeitos dos fármacos , Plasmodium vivax/citologia , Plasmodium vivax/efeitos dos fármacos , Antimaláricos/administração & dosagem , Antimaláricos/uso terapêutico , Camboja , Dapsona/farmacologia , Dapsona/uso terapêutico , Combinação de Medicamentos/farmacologia , Combinação de Medicamentos/uso terapêutico , Resistência Microbiana a Medicamentos , Quimioterapia Combinada , Feminino , Humanos , Masculino , Primaquina/farmacologia , Primaquina/uso terapêutico , Pirimetamina/farmacologia , Pirimetamina/uso terapêutico , Quinina/farmacologia , Quinina/uso terapêutico , Sulfadoxina/farmacologia , Sulfadoxina/uso terapêutico
9.
Bull Soc Pathol Exot Filiales ; 76(4): 357-63, 1983.
Artigo em Francês | MEDLINE | ID: mdl-6605207

RESUMO

39 members of a medical team working in an area near the Cambodia-Thaï border were given an individual antimalaria chemoprophylaxis by Mefloquine (2 tablets--500 mg--every other week), carried on for 2 months after return. Two falciparum accesses were reported after the return, and in one of them, there was also a failure of the Mefloquine treatment (1,5 g in 16 hours). This access was successfully treated by Naphtyridine. The results proved that Mefloquine is now the best individual chemoprophylaxis in this area of South East Asia where, from 1979 to 1981, the other prophylaxis failed (chloroquine, pyrimethamine + sulphonamide or sulfone, quinine); it was also discovered that some strains of P. falciparum were resistant to Mefloquine.


Assuntos
Antimaláricos/uso terapêutico , Malária/prevenção & controle , Quinolinas/uso terapêutico , Adulto , Camboja , Feminino , Humanos , Malária/tratamento farmacológico , Masculino , Mefloquina , Pessoa de Meia-Idade , Quinolinas/efeitos adversos , Tailândia
10.
Med Trop (Mars) ; 43(2): 177-80, 1983.
Artigo em Francês | MEDLINE | ID: mdl-6345984

RESUMO

A biological and clinical survey was conducted in 25 patients with bancroftian filariasis, consulting the El Nikhela Health Centre, Assiout Governorate, Upper Egypt. Eleven patients showed asthmatic bronchitis. According to parasitological and serological data (specific antibodies level, total IgE), those clinical manifestations cannot be considered as a part of the "eosinophilic lung" syndrome. In this area, where Wuchereria bancrofti has been recently introduced and where there is an increasing degree of infection, bancroftian filariasis seems to predispose to allergic manifestations.


Assuntos
Asma/complicações , Filariose/complicações , Adolescente , Adulto , Fatores Etários , Asma/diagnóstico , Diagnóstico Diferencial , Egito , Feminino , Humanos , Imunoglobulina E/análise , Masculino , Eosinofilia Pulmonar/diagnóstico , Fatores Sexuais , Wuchereria bancrofti
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