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1.
Odontol. sanmarquina (Impr.) ; 24(3): 285-290, jul.-sept. 2021.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1255465

RESUMO

El hemangioma lobular capilar es una hiperplasia inflamatoria en respuesta a una irritación crónica, la cual da lugar a una lesión exofítica eritematosa debido a la proliferación de tejido fibrovascular. En la boca puede verse en cualquier ubicación, pero es más frecuente en la zona gingival. Se reporta el caso clínico de una paciente embarazada de 38 años que consultó al equipo de Cirugía Maxilofacial del Hospital San José al presentar una lesión tumoral compatible con hemangioma lobular capilar en cara lingual lateral derecha, diagnóstico confirmado con histopatología. El objetivo de este reporte es especificar características y tratamiento de dicha lesión con localización infrecuente.


Lobular capillary hemangioma is an inflammatory hyperplasia in response to chronic irritation, resulting in an exophytic erythematous lesion due to proliferation of fibrovascular tissue. Intraorally, it can appear in any location, but it is more frequent in the gingival region. This article describes a case of a 38-year-old pregnant woman who at- tended the Maxillofacial Surgery Unit at San José Hospital, presenting a tumoral lesion on the right lateral area of the tongue compatible with a lobular capillary hemangioma. The diagnosis was confirmed with histopathology. The aim of this report is to specify the characteristics and treatment of a lesion with infrequent location.

2.
Med Eng Phys ; 30(9): 1193-200, 2008 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18406195

RESUMO

Blood flow dynamics has an important role in atherosclerosis initiation, progression, plaque rupture and thrombosis eventually causing myocardial infarction. In particular, shear stress is involved in platelet activation, endothelium function and secondary flows have been proposed as possible variables in plaque erosion. In order to investigate these three-dimensional flow characteristics in the context of a mild stenotic coronary artery, a whole volume PIV method has been developed and applied to a scaled-up transparent phantom. Experimental three-dimensional velocity data was processed to estimate the 3D shear stress distributions and secondary flows within the flow volume. The results show that shear stress reaches values out of the normal and atheroprotective range at an early stage of the obstructive pathology and that important secondary flows are also initiated at an early stage of the disease. The results also support the concept of a vena contracta associated with the jet in the context of a coronary artery stenosis with the consequence of higher shear stresses in the post-stenotic region in the blood domain than at the vascular wall.


Assuntos
Algoritmos , Velocidade do Fluxo Sanguíneo , Pressão Sanguínea , Estenose Coronária/fisiopatologia , Vasos Coronários/fisiopatologia , Modelos Cardiovasculares , Reologia/métodos , Animais , Volume Sanguíneo , Simulação por Computador , Humanos , Imageamento Tridimensional/métodos
3.
J Med Eng Technol ; 28(3): 95-103; discussion 104, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-15204613

RESUMO

Grafts used in aortic valve-sparing procedures should ideally not only reproduce the geometry of the natural aortic root but also its material properties. Indeed, a number of studies using the finite element method have shown the importance of the natural sinus shape of the root in the functioning of the normal aortic valve, and the relative increase in stresses due to the replacement of the valve by a stiffer synthetic graft. Because of the wide range in experimentally measured values of aortic wall and leaflet material properties, studies by different research groups have incorporated very different material properties in their models. The aim of the present study was to investigate the influence of material properties on aortic wall displacements, and to determine which material properties would most closely match reported experimental data. Two geometrically accurate 3D models corresponding to the closed and open valve configurations were created in Pro/Engineer CAD software. Loads corresponding to systolic and diastolic pressures were specified and large-displacement structural analyses were carried out using the ANSYS package. Results have indicated that the closest match to experiments using isotropic material properties occurred for a Young's modulus of about 2000 KPa. Nonlinear models based on experimental stress-strain curves have shown similar displacements, but altered strain distribution patterns and significantly lower stresses. These results suggest that an accurate comparison of potential new graft models would have to be made with natural aortic valve models incorporating nonlinear material behavior.


Assuntos
Valva Aórtica/fisiologia , Simulação por Computador , Modelos Biológicos , Valva Aórtica/anatomia & histologia , Diástole , Elasticidade , Análise de Elementos Finitos , Próteses Valvulares Cardíacas , Humanos , Estresse Mecânico
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