Autocrine modulation of glucose transporter SGLT2 by IL-6 and TNF-alpha in LLC-PK1 cells

We determined in cultured kidney epithelial cells (LLC-PK1) the effects of high glucose, interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha) on mRNA and protein expression of the renal glucose transporters SGLT1 and SGLT2. Cultured monolayers were incubated with similar concentrations of IL-6 and (..) (AU)