1.
Haematologica
; 92(4): 570-1, 2007 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17488674
RESUMO
Doxorubicin-loaded erythrocytes (DLE) were administrated to 15 lymphoma patients. Antibiotic peak concentration in blood decreased by 55%, doxorubicin circulated several times longer, and the area under the concentration-time curve increased 5 times if compared with standard doxorubicin administration. The DLE was well tolerated by patients.