1.
Molecules
; 14(9): 3694-9, 2009 Sep 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19783952
RESUMO
A new nor-cardenolide, named toxicarioside H (1), was isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceae). Its structure was elucidated on the basis of HRFAB-MS and spectroscopic techniques (IR, UV, 1D and 2D NMR). Compound 1 showed significant cytotoxicity against K562, SGC-7901, SMMC-7721, and HeLa cell lines in vitro by MTT method.
Assuntos
Antiaris/química , Cardenolídeos/isolamento & purificação , Cardenolídeos/farmacologia , Glicosídeos Cardíacos/isolamento & purificação , Glicosídeos Cardíacos/farmacologia , Látex/química , Morte Celular/efeitos dos fármacos , Linhagem Celular Tumoral , Humanos , Espectroscopia de Ressonância Magnética
2.
J Asian Nat Prod Res
; 11(9): 832-7, 2009 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20183332
RESUMO
Two new cardenolides, toxicarioside F (1) and toxicarioside G (2), were isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceae). Their structures were elucidated on the basis of spectral data and chemical evidence. Compounds 1 and 2 showed significant cytotoxicity against K562, SGC-7901, SMMC-7721, and HeLa cell lines in vitro by the MTT method.
