The Construction of Novel Spirocyclic Frameworks with Cyclobutane through Rh(III)-Catalyzed [3 + 2]-Annulation between Quinoxalines and Alkynylcyclobutanols.

An effective synthesis strategy for the preparation of 1'H-spiro[indene-1,2'-quinoxaline] has been developed. This involves a Rh(III)-catalyzed [3 + 2]-annulation of quinoxalines with alkynylcyclobutanols. The developed protocol offers a straightforward method for the preparation of versatile heterocyclic compounds with a four-membered ring and is compatible with a wide range of functional groups.

Formation of Fluorovinyl Spiro-[imidazole-indene] and α-Amino-ß-naphthalenones via Rh(III)-Catalyzed Cascade C-H Functionalization.

An efficacious method for building fluorovinyl spiro-[imidazole-indene] and α-amino-ß-naphthalenone skeletons synchronously has been shown to consist of Rh(III)-catalyzed C-H functionalization between 2H-imidazoles and difluoromethylene alkynes. This protocol demonstrates a practical and straightforward route for installing fluorine elements in the envisioned position of heterocyclic compounds.