Photoredox-Mediated Synthesis of Functionalized Sulfoxides from Terminal Alkynes.

A photoredox-mediated protocol for the synthesis of α-alkoxy-ß-ketosulfoxides and α,ß-dialkoxysulfoxides using alkynes, thiol, and alcohols is reported. This work presents a rare single-step synthesis of α-substituted sulfoxides, involving tandem introduction of a thiol and alcohol as a key enabling advancement. Furthermore, the method can be easily employed to access vinyl sulfoxides and ß-ketosulfoxides.