RESUMO
BACKGROUND: Periodontitis is a chronic inflammatory disease, and the persistent inflammatory state it confers may lead to cardiovascular disease. Studies have shown that `Life's Essential 8 (LE8)`, an indicator of cardiovascular health, was associated with the risk of several inflammatory diseases. This study aimed to assess the association between LE8 and its subsets and the risk of periodontitis. METHODS: Data of participants who consented to periodontitis examinations were extracted from the National Health and Nutrition Examination Surveys (NHANES) database (2009-2014). LE8 contains 4 health behaviours (diet, physical activity, nicotine exposure, sleep health) and 4 health factors (body mass index, blood lipids, blood glucose, and blood pressure) and was categorised into low (0-49), moderate (50-79), and high (80-100) levels. Covariates included demographic information, laboratory values, disease history, and medication history. Weighted univariate and multivariate logistic regression models were performed to assess the association between LE8 and periodontitis, with odds ratios (ORs) and 95% confidence intervals (CIs). Subgroup analyses based on age, gender, and cardiovascular disease (CVD) history were further assessed the association. RESULTS: A total of 5106 adults were included, of whom 2606 (51.04%) had periodontitis. After adjustment for age, gender, race, poverty-to-income ratio, education level, marital status, drinking, CVD, nonsteroidal anti-inflammatory agents, waist circumference (WC), vitamin D, and dental floss using, a high LE8 score (odds ratio [OR], 0.48; 95% confidence interval [CI], 0.32-0.73), a higher health behaviours score (OR, 0.56; 95% CI, 0.42-0.73), and a higher health factors score (OR, 0.71; 95% CI, 0.51-0.99) were associated with a lower occurrence of periodontitis, especially in adults who were male, younger than 60 years, and without a history of CVD. Moreover, the occurrence of periodontitis decreased when scores of total LE8, health factors, and health behaviours increased every 10 scores. CONCLUSIONS: LE8 score and its subscale scores were associated with lower odds of periodontitis. Promoting improved cardiovascular health may be beneficial to reduce the burden of periodontitis.
RESUMO
PURPOSE: Use of three-dimensional finite element to analyze stress distribution and transient displacement of mandibular first molar both at the occlusal surface level, to investigate the biomechanical basis of vertical root fracture occurring in the mesial root. METHODS: Mimics finite element software was used to build the horizontal and tilt abrasion of the mandibular first permanent molar. Each status was then divided into 4 kinds of wearing degree and 8 models were then established including sliced 1, sliced 2, sliced 3, sliced 4 and miter 5°,miter10°,miter15°,miter20° respectively. 200 N of bite force was loaded on the occlusal surface using MSC. Marc nonlinear finite element analysis software was used to investigate the distribution of stress and transient displacement. RESULTS: When distal tipping angle of the abrasion plane of mandibular first molar increased from 5° to 15°, the angle between instant displacement contours and tooth long axis become smaller, the mesial root suffered from the biggest stress concentration and thus the possibility of longitudinal root fracture increased. CONCLUSIONS: When the abrasion plane of mandibular first molar tilted distally, the possibility of the mesial root longitudinal fracture increased.
