RESUMO
Recently, ultrathin localized spoof surface plasmon (LSSP) resonators are found to have intrinsic defects of relatively low quality factors (Q-factors) because of unavoidable material and radiation losses. In this paper, multilayer structures of planar-circular-grating resonators and their magnetic-coupling schemes are proposed to achieve effective excitation of high-Q LSSPs modes. By adopting the multilayer structures with air between the layers, the power dissipation effected by both material and radiation losses is significantly suppressed. Experimental results show that the Q-factors could reach more than 200 and the excitation efficiencies could reach more than 90%. Numerical simulations show the distribution of the electromagnetic field and illustrate the principle of magnetic coupling. Besides, the Q-factors of resonators with different structural parameters were measured and analyzed. This study aims to provide some inspirations on planar gyro-devices and to improve the performance of existing applications, such as sensors and filters.
RESUMO
Monoclonal antibodies (mAbs) have become increasingly important as human therapeutic agents. Yet, current research concentrates on technology itself and pays attention to developed countries. This paper aims to provide a comprehensive review of mAbs development in China through systematic analysis of drug registry, patent applications, clinical trials, academic publication, and ongoing R&D projects. The trends in therapeutic areas and industrialization process are also highlighted. Development and research trends of mAbs are analyzed to provide a future perspective of mAbs as therapeutic agents in China.
