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Neirofiziologiia ; 22(6): 780-6, 1990.
Artigo em Russo | MEDLINE | ID: mdl-2097505

RESUMO

Taurine-activated currents in isolated neurons of the rat cerebellum were studied by voltage and "concentration" clamp methods. They were transmitted by potassium and chloride ions. The dose-response curve with the dissociation constant 2 x 10(-3) mol/l was obtained. The cross-desensitization between taurine and GABA, but not between taurine and glycine was shown. These currents were also blocked by bicucullin and strychnine, but in a different manner.


Assuntos
Células de Purkinje/efeitos dos fármacos , Células de Purkinje/fisiologia , Taurina/farmacologia , Animais , Bicuculina/farmacologia , Relação Dose-Resposta a Droga , Interações Medicamentosas , Técnicas In Vitro , Potenciais da Membrana/efeitos dos fármacos , Potenciais da Membrana/fisiologia , Oxazepam/farmacologia , Pentobarbital/farmacologia , Ratos , Estricnina/farmacologia
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