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1.
Mem Inst Oswaldo Cruz ; 98(5): 703-8, 2003 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-12973541

RESUMO

Since the reintroduction of Aedes aegypti in the state of S o Paulo, in the middle of the 1980-decade, organophosphate insecticides are being used to control the dengue vector. In 1996, an annual program for monitoring the susceptibility of Ae. aegypti to the insecticides was implemented. Some of the results of this monitoring program are presented. Ae. aegypti populations from ten localities have been submitted to bioassays with the diagnostic dose of temephos and fenitrothion. Only two (Mar lia and Presidente Prudente) remain susceptible to both insecticides and one (Santos) exhibits true resistance. Ae. aegypti from the remaining localities showed an incipient altered susceptibility. Resistance ratios varied from 1.2 to 2.9 for temephos and from 1.5 to 3.2 to fenitrothion, indicating moderate levels of resistance. Biochemical assays did not detect alterations in the enzyme acetilcholinesterase, but indicated that resistance is associated with esterases.


Assuntos
Aedes/efeitos dos fármacos , Fenitrotion/farmacologia , Inseticidas/farmacologia , Temefós/farmacologia , Aedes/enzimologia , Animais , Bioensaio , Brasil , Dengue/prevenção & controle , Esterases/metabolismo , Resistência a Inseticidas , Larva/efeitos dos fármacos , Larva/enzimologia , Controle de Mosquitos
2.
Mem. Inst. Oswaldo Cruz ; 98(5): 703-708, July 2003. mapas, tab, graf
Artigo em Inglês | LILACS, Sec. Est. Saúde SP | ID: lil-344293

RESUMO

Since the reintroduction of Aedes aegypti in the state of Säo Paulo, in the middle of the 1980-decade, organophosphate insecticides are being used to control the dengue vector. In 1996, an annual program for monitoring the susceptibility of Ae. aegypti to the insecticides was implemented. Some of the results of this monitoring program are presented. Ae. aegypti populations from ten localities have been submitted to bioassays with the diagnostic dose of temephos and fenitrothion. Only two (Marília and Presidente Prudente) remain susceptible to both insecticides and one (Santos) exhibits true resistance. Ae. aegypti from the remaining localities showed an incipient altered susceptibility. Resistance ratios varied from 1.2 to 2.9 for temephos and from 1.5 to 3.2 to fenitrothion, indicating moderate levels of resistance. Biochemical assays did not detect alterations in the enzyme acetilcholinesterase, but indicated that resistance is associated with esterases


Assuntos
Animais , Temefós , Aedes , Inseticidas Organofosforados , Fenitrotion , Bioensaio , Brasil , Resistência a Inseticidas , Controle de Mosquitos , Aedes , Dengue , Esterases , Larva
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