Pre-Exposure Prophylaxis, Anxiety, Depression and Sexual SatisfactionAmong Men Who Have Sex With Men

BACKGROUND: Pre-exposure prophylaxis (PrEP) has been implemented as a prevention against HIV; however, its impact on mental health, sexual and life satisfaction has not been addressed. METHOD: We assessed 114 HIV-negative participants from Spain with ages ranging from 19 to 58 years; 60.5% were PrEP users ( n = 69) and 39.5% were non-users ( n = 45). They completed five questionnaires about life and sexual satisfaction, depression and anxiety. We performed correlations and multiple regression analyses. RESULTS: The PrEP group showed a statistically significant relationship between better sexual satisfaction, and greater life satisfaction. The PrEP group also showed a statistically significant negative relationship with depression and anxiety which was not found in PrEP non-users. Moreover, we found that younger PrEP users had higher scores in anxiety and lower scores in depression than older users. The hierarchical regression analyses also showed that number of sexual partners was a major predictor in the PrEP group for NSSS. CONCLUSIONS: The indirect correlation between sexual satisfaction, depression, and anxiety in the PrEP group could underly the benefits of PrEP for patients' sex lives such as increased sexual liberties due to lower anxiety and mental comfort when experiencing chemsex.

Pre-Exposure Prophylaxis, Anxiety, Depression and Sexual Satisfaction Among Men Who Have Sex With Men / Profilaxis Pre-Exposición, Ansiedad, Depresión y Satisfacción Sexual en Hombres que Tienen Sexo con Otros Hombres

Background: Pre-exposure prophylaxis (PrEP) has been implemented as a prevention against HIV; however, itsimpact on mental health, sexual and life satisfaction has not been addressed. Method: We assessed 114 HIV-negativeparticipants from Spain with ages ranging from 19 to 58 years; 60.5% were PrEP users (n = 69) and 39.5% werenon-users (n = 45). They completed five questionnaires about life and sexual satisfaction, depression and anxiety. Weperformed correlations and multiple regression analyses. Results: The PrEP group showed a statistically significantrelationship between better sexual satisfaction, and greater life satisfaction. The PrEP group also showed a statisticallysignificant negative relationship with depression and anxiety which was not found in PrEP non-users. Moreover, wefound that younger PrEP users had higher scores in anxiety and lower scores in depression than older users. Thehierarchical regression analyses also showed that number of sexual partners was a major predictor in the PrEP group forNSSS. Conclusions: The indirect correlation between sexual satisfaction, depression, and anxiety in the PrEP groupcould underly the benefits of PrEP for patients’ sex lives such as increased sexual liberties due to lower anxiety andmental comfort when experiencing chemsex.

Antecedentes: El impacto de la profilaxis pre-exposición (PrEP) sobre la salud mental, así como en la satisfacción sexualy con la vida son aún desconocidas. Método: Analizamos 114 participantes VIH negativos de España con rango de edad[19-58 años], donde el 60,5% eran usuarios de PrEP (n = 69) y el 39,5% no (n = 45). Completaron cinco tests sobre lasatisfacción sexual y con la vida, la depresión y la ansiedad. Realizamos correlaciones y análisis de regresión múltiple.Resultados: El uso de PrEP correlacionó con un incremento de la satisfacción sexual y con la vida. Mostraron unacorrelación negativa en depresión y ansiedad que no se observó en los no consumidores de PrEP. Los usuarios de PrEPmás jóvenes mostraban puntuaciones más altas en ansiedad y más bajas en depresión que los de mayor edad. Los análisisde regresión jerárquica mostraron que el número de parejas sexuales fue un predictor importante en el grupo de PrEP parala NSSS. Conclusión: La correlación indirecta entre la satisfacción sexual, la depresión y los síntomas de ansiedad en losusuarios de PrEP, podría ser la base de los beneficios que la PrEP puede ofrecer a la vida sexual de los pacientes.(AU)

Iodine nutritional status in pregnant women of two historically different iodine-deficient areas of Catalonia, Spain.

OBJECTIVE: Catalonia (Spain) has a historically worse situation of mild iodine deficiency in the Pyrenees Mountains compared with the coastal region. The aim of this study was to evaluate the current iodine status in pregnant women living in these two areas. METHODS: An epidemiologic prospective survey included 267 consecutive pregnancies in the Catalan mountains (n = 139) and coast (n = 128) studied during the first trimester; an additional subset of 135 women from the initial cohort was available for evaluation in the third trimester. Urinary iodine (UI) was measured, and questionnaires to determine iodized salt and sea fish consumption and potassium iodide supplementation were administered. RESULTS: The median UI in the first trimester was 163 µg/L for the entire cohort, with differences between mountain and coastal regions (209 versus 142 µg/L, P = 0.007). The highest prevalence of iodized salt consumption was in the mountain area (58% versus 36.4%, P < 0.001). For the entire group, a higher median UI was found in iodized salt consumers compared with non-consumers (193 versus 134 µg/L, P < 0.001). In the third trimester, an increase of median UI was seen in those to whom iodine supplements were given during pregnancy (190 versus 154 µg/L, P = 0.015). CONCLUSION: A reversal in the historically iodine-deficient situation was observed in the Catalan Pyrenees compared with the coastal area, with a globally acceptable iodine status in pregnant women of the two geographic locations. Iodized salt consumption seems to have contributed to maintaining an acceptable iodine status in this population.

Estreptococo Beta hemolítico del grup "b", reporte de os casos comprobados bacteriológicamente de sépsis neonatal en Guatemala

La sepsis neonatal es una de las causas de mayor mortalidad en las salas de recién nacidos y entre los agentes causales, el Streptococcus Beta hemolítico del grupo "B", es uno de los micro organismos más importantes. La fiebre puerperal y la ruptura temprana de membranas son complicacioens obstétricas que se conocen puedan ser causadas por el estreptococo Beta hemolítico del grupo "B". Por el presente informe se aportan datos clínicos más relevantes y las técnicas microbiológicas utilizadas que permitieron el aislamiento del microorganismo motivo del presente trabajo. Se discuten las probables causas de la baja incidencia de sepsis neonatal por el estreptococo Beta hemolítico del grupo B en Guatemala. Se informa por primera vez los aislamientos de Streptococcus Beta hemolítico del grupo B en Guatemala. Se informa por primera vez los aislamientos de Streptococcus Beta hemolítico del grupo B de Lancefield a partir de cultivos de sangre y también el hallazgo de esta bacteria en otros sitios de infección, tanto en los recién nacidos como en las madres