RESUMO
La hidrosadenitis supurativa es una enfermedad inflamatoria crónica que afecta a las glándulas apocrinas. Al igual que en otras enfermedades inflamatorias crónicas de la piel pueden producirse cambios degenerativos. El carcinoma escamoso es la neoplasia maligna descrita con más frecuencia siendo excepcional el hallazgo de su variedad bien diferenciada denominado carcinoma verrucoso. Desde 1988, en nuestro hospital se han intervenido 44 pacientes diagnosticados de hidrosadenitis supurativa, de los cuales 15 presentaban una forma masiva de la enfermedad. Durante este periodo tan solo un paciente atendido en nuestra unidad de coloproctología por afectación perianal presentó degeneración maligna hacia un carcinoma verrucoso. Presentamos este caso y comentamos las peculiaridades clínicas y terapeúticas de esta situación tan poco frecuente (AU)
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Assuntos
Feminino , Pessoa de Meia-Idade , Humanos , Carcinoma Verrucoso/diagnóstico , Hidradenite/complicações , Neoplasias Cutâneas/diagnóstico , Carcinoma Verrucoso/complicações , Carcinoma Verrucoso/cirurgia , Carcinoma Verrucoso/patologia , Glândulas Apócrinas/patologia , Hidradenite/cirurgia , Hidradenite/diagnóstico , Diagnóstico Clínico , Neoplasias Cutâneas/cirurgia , Neoplasias Cutâneas/complicações , Neoplasias Cutâneas/patologiaRESUMO
To determine if employment within a petrochemical plant's quality control (QC) laboratory had any significant effect on the hematopoietic system, and in specific, the white blood cell (WBC) counts, all employees of the QC laboratory were evaluated retrospectively. Trend analysis, linear regression, and Students t tests were performed on all employees of the QC laboratory and on a simple random sample of the rest of this Caribbean petrochemical plant's male employees. Trend analyses revealed a downward trend in 82.6% of the QC laboratory workers and 76.7% in other plant workers. Linear regression and t tests revealed no statistically significant difference by worksite but a significant difference between blacks and whites. The result of the findings of the QC laboratory workers was consistent with that expected in both plant employees and the US general population. A recommendation is made that the Occupational Safety and Health Administration (OSHA) reconsider its WBC cutoff level in the benzene standard.
