1.
Ther Drug Monit
; 2024 Jun 26.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38950121
RESUMO
BACKGROUND: The case study discusses a complex scenario involving the use of amoxicillin in a critically ill patient undergoing intermittent renal replacement therapy.Severe infections are complicated by septic shock and organ failure, requiring urgent and effective antibiotic treatment. METHODS: The patient's comorbidities, including obesity and acute kidney injury, required careful consideration of the amoxicillin dosing strategies. RESULTS: Therapeutic drug monitoring is critical for dose adjustment during treatment. CONCLUSIONS: This case highlights the importance of a collaborative approach between clinicians and therapeutic drug monitoring consultants to optimize antibiotic therapy for critically ill patients with renal impairment.