[Complete amino acid sequence of neurotoxin Os-1 from the venom of the Central Asian black scorpion Orthochirus scrobiculosus]. / Polnaia aminokislotnaia posledovatel'nost' neirotoksina Os-1 iz iada sredneaziatskogo chernogo skorpiona Orthochirus scrobiculosus.

The neurotoxin Os-1 from the venom of the Central Asian scorpion Orthochirus scrobiculosus possesses a high paralytic activity against mice. This neurotoxin was subjected to tryptic, chymotryptic and BrCN cleavages and its total amino acid sequence was established. It was shown that neurotoxin Os-1 consists of 66 amino acid residues an contains four disulfide bonds.

[Neurotoxins from the venom of the Central Asian scorpion Buthus eupeus]. / Izuchenie neirotoksinov iz iada sredneaziatskogo skorpiona Buthus eupeus.

Three main polypeptide neurotoxins M9, M10, M14, possessing paralytic activity in mice, have been isolated from the venom of the Central Asian scorpion Buthus eupeus. The amino acid composition of these toxins was determined. Toxins M9 and M14 were digested with trypsin, chymotrypsin, Staphylococcus aureus proteinase and cleaved with BNPS-skatole. The complete amino acid sequences of the toxins M9 and M14 were established.

[Amino acid sequence of 2 neurotoxins from the scorpion Buthus eupeus venom]. / Aminokislotnaia posledovatel'nost' dvukh neirotoksinov iz iada skorpiona Buthus eupeus.

Three polypeptides, M10, M14 and M9, toxic to mammals were isolated from the venom of the Central Asian scorpion Buthus eupeus. All the toxins were shown to be homogeneous according to disc-electrophoresis and N-terminal group analyses. The toxin M9 was digested with trypsin, Staphylococcus aureus proteinase and cleaved with BNPS-skatole. The toxin M14 was subjected to tryptic and chymotryptic hydrolyses. The complete amino acid sequences of the toxins M9 and M14 were established and it was shown that each of them consists of 66 amino acid residues with four intramolecular disulfide bonds.