Ulcerative and oral lichen planus associated with sicca syndrome and primary biliary cirrhosis.

The following case report supports the hypothesis that the coexistence of lichen planus, primary biliary cirrhosis, and sicca syndrome is not co-incidental. The fact that all three diseases are manifest in the same patient substantiates a theory of pathogenesis based on a cell-mediated immune response analogous to that in allogeneic bone marrow transplant recipients with chronic graft-versus-host disease.

Mycobacterial skin disease: approaches to therapy.

Many mycobacteria, including M tuberculosis, M leprae, and several atypical organisms, produce skin disease. Chemotherapy is necessary for most infections. Surgery may be helpful for some atypical infections.