1.
Bull Exp Biol Med
; 158(4): 450-2, 2015 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25708323
RESUMO
We compared anti-IIa activity of a heparin analogue and a reference product was carried out to confirm their biosimilarity. The experiment was based on the method of estimation of anti-IIa activity of a commercial sodium heparin preparation according to United States Pharmacopoeia. High similarity of the two medicinal heparin preparations by this parameter is shown. The method is recommended for the use in comparability studies.