[The outlook for the creation of a bank of cryopreserved cord blood for clinical use]. / Perspektiva sozdaniia banka kriokonservirovannoi kordovoi krovi dlia klinicheskogo primeneniia.

Appraisal of morphological and functional features of cord blood cells involving identification of precursor cells marked with specific monoclonal antibodies makes it possible to regard cord blood as biologically valuable hemopoietic tissue with a high repopulation potential. Studies aimed at developing optimal conditions of cryopreservation allow the stocks of biologically valuable tissue to be built up.

[The criteria of disorders in body antitumor resistance in subjects with dyshemopoiesis]. / Kriterii narushenii protivoopukholevoi rezistentnosti organizma u lits s disgemopoézom.

A complex of methods is proposed adapted to practices common in clinical and diagnostic laboratories that enables the state of bodily antitumoral resistance to be properly assessed. A diagnostic system of disturbances in the antineoplastic resistance of the organism, which makes for detection of endogenous factors marking a high risk for the development of oncohemopathology is suggested.

[The efficacy of active specific immunotherapy using modified neoplastic cells in the combined modality treatment of hemoblastoses]. / Effektivnost' aktivnoi spetsificheskoi immunoterapii modifitsirovannymi neoplasticheskimi kletkami v kompleksnom lechenii gemoblastozov.

Efficiency was studied of active specific immunotherapy (IT) with cell vaccine consisting of allogenic viable cryopreserved modified Con A blast cells identical with the illness in patients with acute myeloblastic leukemia and acute lymphoblastic leukemia. The studies made confirmed a positive impact of IT on the clinical course of acute leukosis (prolonged remission, keeping down infectious complications), on leukopoiesis, peripheral blood cells enzymatic status as well as on cell immunity, certain factors of humoral immunity and bodily natural antineoplastic resistance.

[The criteria for forming risk groups among the population exposed to ionizing radiation after the accident at the Chernobyl Atomic Electric Power Station]. / Kriterii formirovaniia grupp riska sredi naseleniia, podvergshegosia vozdeistviiu ioniziruiushchego izlucheniia posle avarii na Chernobyl'skoi AES.

Studied were particular features of peripheral blood, certain immunological and biochemical indices under long-term exposure of human body to radiation after the accident at the Chernobyl Nuclear Power Plant. The study comprised 5578 individuals. The examinees were liquidators of the Chernobyl accident sequels (n = 1052), inhabitants of Pripyat evacuated from the town (n = 850), the Kiev SSBT primary donors (n = 1738). Control group consisted of 936 Kievans who had been examined before the accident between 1982-1985 by the same methods. The results obtained allowed for the most informative indices to be found in order that risk groups might be formed.

[The results of studies of the peripheral blood from children in Polesie District, Kiev Province and in the city of Kiev 4 years after the accident at the Chernobyl Atomic Electric Power Station]. / Rezul'taty issledovanii perifericheskoi krovi detei Polesskogo raiona Kievskoi oblasti i g. Kieva cherez chetyre goda posle avarii na Chernobyl'skoi AES.

The peripheral blood of 2200 children (age: from 2 to 16 years) inhabiting the Polessye District of Kiev Province and the city of Kiev 4 years after the Chernobyl atomic station accident was studied. An analysis of results revealed the presence of hematologic changes that may be interpreted as sequels of the effect of ionizing radiation on the body, while other changes may be considered as reactive and may in most cases accompany different somatic diseases of infectious-inflammatory character.