[Post exertion bronchospasm--usefulness of different methods for evaluating bronchial constriction after exertional provocation]. / Powysilkowy skurcz oskrzeli--przydatnosc róznych metod oceny droznosci dróg oddechowych po prowokacjach wysilkowych.

55 children with bronchial asthma were tested using three exercise provocation tests: a treadmill, stairways running and cycloergometer. The results were evaluated on the base of the lung function tests, auscultation and airways resistance measurement with occlusion method. Of these three tests the treadmill test seemed to be the most useful to prove bronchial hyperreactivity towards exercise. Stairways running occurred to be very congenial. The study also proved usefulness of auscultation in evaluating of bronchial constriction after exercise.

[Comparison of the effect of two budesonide preparations for treatment of bronchial asthma in children]. / Porównanie efektywnosci dwóch preparatów budezonidu w leczeniu astmy oskrzelowej u dzieci.

In a group of 55 children in the age of 7-14 years with mild or severe asthma, the evaluation of inhaled budesonide (in pulmicort and horacort) effect on bronchial reactivity and adrenal cortex function was made. Budesonide in dose 640 mg or 800 mg daily was administered during 6 weeks. In addition fenoterol was administered in dose 2 x 200 mg daily. Lung function tests, a histamine provocation and cortisol level in serum were done before, after 2 weeks and after 6 weeks in the course of treatment. Effective control upon the disease was observed in 67.9% and 70.4% patients. The result of the treatment was significant decrease in bronchial reactivity toward a histamine. Decrease of FEV1-32% and -34% in the first study was improved after two weeks up to -24% and -17% and after six weeks it achieved-12%. The level of endogenous cortisol in serum didn't show significant decrease in the course of therapy. The ratio of benefits and risk of side effects in the course of budesonide in medium dose during six weeks indicates clearly the first ones.

[Spirographic studies and measurement of airflow resistance in evaluation of bronchial hyperreactivity in children with asthma]. / Badanie spirograficzne i pomiar oporów w drogach oddechowych w ocenie nadreaktywnosci oskrzeli u dzieci z astma.

An analysis of spirographic studies and measurement of airflow resistance in diagnosing bronchial hyperreactivity in 27 children with bronchial asthma was made. Histamine was used for provocation tests. Bronchial hyperreactivity was found in 85.2% of the studied children. The most useful for predicting existence of bronchial hyperreactivity proved to be FEV1, FEV, and PEF measurements. After histamine provocation airflow resistance rose from 0.42 kPa/l/s to 0.63 kpa/l/s. that is by 50%. Both tests spirometric and airflow resistance proved to be comparable in 70.4%. Usage of both methods allows a better chance of diagnosing bronchial hyperreactivity.