[Bone marrow monosomy 7 in children]. / Monosomie 7 médullaire chez l'enfant.

Three new cases of monosomy 7 are described. Two children, before onset of overt leukemia, had a preleukemic state: one with thrombopathy and myelodysplastic syndrome, the other with a moderate splenomegaly and an absolute monocytosis. In these two cases the leukemia was chemoresistant. The last child had a subacute myelomonocytic syndrome (juvenile type of chronic myelogenous leukemia) without high fetal hemoglobin value. She died from cachexia. The poor prognosis of monosomy 7 is underlined and such a chromosome deletion should be searched in myeloproliferative syndrome with monocytosis.

[A rare cause of hydrocephalus in an infant: chronic vitamin A poisoning]. / Une cause rare d'hydrocéphalie du nourrisson: l'intoxication chronique par la vitamine A.

A case of chronic vitamin A intoxication is reported in an infant under 6 months of age. The features included hydrocephalus, usually described in acute hypervitaminosis A and the other cutaneous, hepatic and skeletal signs observed in chronic intoxication.

[Staphylococcal toxic shock]. / Le choc toxique staphylococcique.

The authors report the case of a 5 year-old child who, after a sore throat, developed gastrointestinal problems, high fever, scarlatinaform rash, conjunctivitis, shock with renal failure and involvement of liver, pancreas and muscles. No infectious site was detected. However, he had positive blood culture for staphylococcus aureus. The child fully recovered after a period of desquamation of the palms and soles.

[Tetanus. Apropos a case]. / Le tétanos. A propos d'un cas.

The authors report a case of tetanus in a 19 months infant who has only received BCG. After a four days period during which two laryngeal spasms occurred, the infant presents a generalized tetanus. The outcome was favorable with specific serotherapy myorelaxants and assisted ventilation of four weeks duration.