[Itraconazole and secnidazole capsules vs. vaginal ovules of fluocinolone acetonide, nystatin and metronidazole in the symptomatic treatment of vaginitis]. / Itraconazol + Secnidazol cápsulas Vs. óvulos vaginales Acetónido de Fluocinolona 0.50 mg, Nistatina 100,000 U y Metronidazol 500 mg en el tratamiento sintomático de la vaginitis.

OBJECTIVE: Evaluation of oral treatment in vaginitis and vaginosis using Itraconazol and sechidazol, in comparison to topic treatment using vaginal ovules of acetonido of fluocinolona 0.50 mg, nistatina 100,000 U and metronidazol 500 mg. DESIGN: Longitudinal, prospective and open comparative study. PLACE: Servicio de Reproducción Humana(Human Reproduction Department), Centro Médico Nacional "20 de Noviembre". MATERIAL AND METHODOLOGY: Forty female patients, without any relevant differences in their general characteristics, chose diagnosis was vaginitis and vaginosis, who were medically treated through external consultation, divided in two groups of twenty each one. Group 1 oral treatment with itraconazol and secnidazol. Group 2 had topic treatment with fluocinolona, nistatina and metronidazol. All of the patients were controlled in seven and fourteen days time, in order to evaluate the intensity of their clinical symptomatology, as well as the efficacy in both ways of treatment. RESULTS: Leukorrhea was the most important symptom in all the cases, going from minor to serious white discharge. After the treatment, we found a relevant difference statistically significative in patients treated with intraconazol and secnidazol. We did not find any differences in relation to ardor, pruritus, dispareunia and disuria at post-treatment evaluation. However, group 1 betterment was statistically significative between the first and the seventh days of treatment. CONCLUSION: Treating vaginitis or vaginosis (or both) with itraconazol and secnidazol takes less time for betterment in addition to comfort and easiness of oral administration; therefore, we consider them proper medicines in these specific cases.

[Alternative management of iron deficiency anemia in pregnancy and puerperium]. / Manejo alternativo de la anemia ferropénica en el estado grávido-puerperal.

An open, observative, prospective, follow-up study was performed in 80 obstetric patients at the 20 de novembre Hospital in Mexico city between november 1986 and august 1987. There were two groups: 40 pregnant patients (between 15 and 35 weeks of pregnancy), and 40 puerperants (between 1st and 6th day or puerperium), both groups had confirmed diagnosis of iron deficiency anaemia; iron-deficiency was estimated upon haemoglobin level, patients body weight and obstetric status. After that, diluted dextran-iron was infused intraveously, six weeks after iron infusion the patients were evaluated. Haemoglobin, haematocrit and red blood cell levels showed a significant rise. Abnormalities observed in the blood smear decreased; 10% of the patients in both groups showed slight secondary reactions, which were self-limited or subside with medical therapy.

[Morbidity and mortality in pregnant patients with lupus erythematosus]. / Morbimortalidad en la paciente lúpica embarazada.

The clinical records of 14 patients with proved diagnosis of sistemic lupus erythematosus (SLE) associated to pregnancy, seen between november 1986, and july 1988 at the "20 de Novembre" Hospital in Mexico City, were studied. The following variables were evaluated: maternal age, of beginning of SLE, lupus criteria present at the moment of the acute phase of the disease, obstetric history, prenatal care, age of pregnancy, laboratory studies, therapy before, during and after delivery, children's findings, and maternal complications, 50% of the patients had history of previous abortions; there was a high incidence of preterm deliveries (42.86%); 71.42% of the patients suffered hypertension; 64.31% had anemia. Therapy was based on corticosteroids and antihypertensive drugs. There was a significant relationship between low hemolitic complement levels and product's weight.