RESUMO
Energy transfer has been employed in third-generation solar cells for the conversion of light into electrical energy. Long-range nonradiative energy transfer from semiconductor quantum dots (QDs) to fluorophores has been demonstrated by using CdS QDs and thiophene-BODIPY (boron dipyrromethene, abbreviated as TG2). TG2 shows a broad photoluminescence (PL) spectrum, which varies with concentration. At very low concentrations, monomeric units are present; then, upon increasing the concentration, these monomers form a mixed (J-/H-)aggregated state. Energy transfer between the CdS QDs and TG2 was confirmed by separately investigating the interactions between CdS and the monomer of TG2 and between CdS and the aggregated states of TG2. Size-dependent PL quenching confirmed that nonradiative Förster resonance energy transfer (FRET) from photoexcited CdS QDs to the J-aggregate state of TG2 was the major energy-relaxation channel, which occurred on the timescale of hundreds of fs. These results have broad applications in the field of light harvesting based on the assembly of molecular aggregates.
RESUMO
We report the first high affinity neutral Bodipy fluorophores for selective imaging of mitochondria with notable sensitivity (â¼100 nM) and insignificant cytotoxicity even at very high concentration (â¼100 µM), when tested against HeLa cells. Further, these fluorophores are chemically robust and require no special conditions for storage.
RESUMO
We report a series of four efficient photosensitizers (PSs) based on a Bodipy core for photodynamic therapy (PDT). In the absence of hydrophilic functional groups, these PSs have been encapsulated in liposomes and examined for photocytotoxicity against human ovarian carcinoma cell line (SK-OV-3). The IC50 values obtained are as low as 0.350 µM, which compete with the classical photosensitizer chlorine E6 (IC50 = 0.39 µM) under similar experimental conditions.
