[Hyperthyroidism associated with hydatid moles]. / Hyperthyroïdies dans les môles hydatiformes.

With reference to a 25-year-old patient who developed manifestations of clinical and paraclinical hyperthyroidism during the course of a molar pregnancy, the authors studied correlations between the two conditions. Hyperthyroidism is the result of hyperstimulation, of placental origin, and disappears when the hyperstimulation disappears. The placenta is capable of producing a TSH-like factor. HENNEN and HERSCHMAN established the existence of human chorionic thyrotropin which has hormonal and physicochemical properties similar to those of TSH, and which has just been isolated by Japanese workers. In fact during the development of a mole, it is molar HCT (or MHCT) that constitutes either a precursor or a subunit of HCT. However, hyperthyroidism remains rare during the course of molar pregnancies, a fact that has not yet been explained.

[The obstetrical and fetal prognosis after metrorrhagia in the first trimester of pregnancy: with reference to 187 cases]. / L'avenir obstetrical et foetal après métrorragies au premier trimestre de la grossesse. A propos de 187 observations.

The authors followed 187 pregnancies in which metrorrhagia had occurred in the first trimester, but which had not resulted in abortion. In these patients, the authors studied particularly changes in hormone levels in the urine and the relation between these levels and fetal prognosis. If hormonal deficit is related to fetal prognosis, the relationship does not appear to be a direct one: estrogen deficiency is discovered more often than luteal deficiency; the more serious the estrogen deficiency the more often is it associated with severe progesterone deficiency; The number of fetal malformations did not seem to be any higher in patients who had presented metrorrhagia in first trimester than in patients whose pregnancy was normal. Any higher in patients who had presented metrorrhagia in the pregnancy on one hormone analysis, whether or not it is abnormal. The examinations should be repeated so that the evolution may be followed carefully.

[Emergency haemostasis hysterectomy in obstetrics]. / Les hystérectomies d'hémostase d'urgence en obstétrique.

The study was based on 15 cases of haemostasis hysterectomy: 7 cases after caesarian section, 8 cases after normal delivery. The etiological circumstances varied, the haemorrhage being due to uterine rupture, to an accident during delivery related to uterine atony, to placenta accreta, or to a coagulation disorder. In these circumstances, the most satisfactory operation seems to be total hysterectomy with bilateral ovariectomy, conservation of the ovaries being justified in younger women. The authors describe the precautions that they feel are essential during labour or during a caesarian section to avoid such complications.

[Lesions associated with uterine fibromas: with reference to 207 cases]. / Les lésions associées au fibrome utérin. A propos de 207 observations.

With reference to 207 observations of lesions associated with uterine fibronias. the authors have tried to discover a distinct anatomo-pathological entity. Associated lesions are found in 31 percent of cases. and this frequency should be particularly noted, when the classical view emphasizes particularly the occurrence of complications. The lesions found in association with this type of fibroma are listed below in order of frequency of occurrence: infectious lesions, ovarian dystrophies, hormonal disorders, benign or malignant tumoral lesions, and endometriosis. Attempts at pre-operative diagnosis have been rather disappointing, as only 41 percent of the cases have been diagnosed. The presence of these associated lesions leads more readily to the use of surgery but it is not easy to determine whether this is because of the existence of the lesions or because they are misunderstood. if the associated lesions are diagnosed before the operation, medical treatment of the lesions, particularly in the case of infectious lesions or endometriosis, does not avoid the need for surgery but often make it easier.

[A clinical, histological, and biochemical study of ovarian arrhenoblastomas: with reference to one case]. / Etude clinique, histologique et biochimique de l'arrhénoblastome de l'ovaire. A propos d'un cas.

The authors review the literature in relation to a detailed study of an ovarian arrhenoblastoma operated on in a young patient who subsequently became pregnant twice, one of these pregnancies developing to full term. This review makes it possible to formulate certain anatomopathological ideas, and above all makes it clear that complete endocrine studies are infrequently carried out. It has been shown in cases of arrhenoblastoma that some of the anomalies of steroidogenesis are secondary to the enzyme disorders, the impression being that, with this kind of tumour, the tumour parenchyma begins to secrete like a normal testicle.

[The pathology of the stump of the uterine cervix]. / La pathologic du col restant.

With reference to 70 patients, the authors studied the pathology of the stump of the cervix left after subtotal hysterectomy. The wide range of disorders presented by women after partial hysterectomy included metrorrhagia (44.2 percent of cases), pelvic pain, leucorrhoea, cervical pain, and functional disorders related to prolapse. Lesions found on the stump of the cervix included: cancer in 15.7 percent of cases, of which the clinical symptoms were not specific to the stump of the cervix: however, the methods of treating such cancers, of the usual methods are used, raise complex problems; prolapse was found after subtotal hysterectomy in 27.1 percent of cases and the symptomatology was not unusual. Here also, the absence of the uterus increases the difficulties of surgery. Thus subtotal hysterectomy appears to present more dangers than advantages and, except in particular cases, the authors prefer total hysterectomy.