1.
Am J Med
; 81(1): 139-42, 1986 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3728540
RESUMO
A patient with severe amegakaryocytic thrombocytopenic purpura was treated with cyclophosphamide and had an excellent response after four weeks. His condition remained in complete remission for at least five months. Acquired amegakaryocytic thrombocytopenic purpura is a rare disorder with several possible causes. An intrinsic defect at the level of the megakaryocyte colony-forming units, or a circulating autoantibody directed against these colony-forming units has been suggested. This patient's response to cyclophosphamide supports the hypothesis of an immune mechanism in some of these cases, and it is recommended that immunosuppressive therapy be further evaluated.
Assuntos
Ciclofosfamida/uso terapêutico , Megacariócitos/patologia , Púrpura Trombocitopênica/tratamento farmacológico , Idoso , Plaquetas , Transfusão de Sangue , Medula Óssea/patologia , Diagnóstico Diferencial , Humanos , Masculino , Púrpura Trombocitopênica/diagnóstico , Púrpura Trombocitopênica/terapia
2.
Kango Gijutsu
; 30(5): 701-6, 1984 Apr.
Artigo
em Japonês
| MEDLINE
| ID: mdl-6563130
3.
Am J Nurs
; 83(1): 78-85, 1983 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-6549725