RESUMO
Epithelioid sarcoma is a rare soft-tissue tumor that occurs mainly in children and young adults. It typically presents as a subcutaneous or deep dermal mass in distal extremities. Due to its benign-appearing clinical presentation, infrequent occurrence, and histologic similarities with other pathologies, the diagnosis of epithelioid sarcoma in its early stages can be extremely difficult and can be easily confused with benign lesions such as warts or foreign body granuloma. In this paper, we report the case of a 12-year-old boy with a distal-type epithelioid sarcoma of the hand and wish to emphasize the difficulties of diagnosing this potentially lethal tumor both clinically and histologically.
Assuntos
Papiloma , Sarcoma , Neoplasias de Tecidos Moles , Verrugas , Criança , Diagnóstico Diferencial , Humanos , Masculino , Sarcoma/diagnóstico , Neoplasias de Tecidos Moles/diagnóstico , Adulto JovemAssuntos
Alopecia/etiologia , Nevo/diagnóstico por imagem , Neoplasias Cutâneas/diagnóstico por imagem , Gordura Subcutânea/diagnóstico por imagem , Alopecia/diagnóstico por imagem , Criança , Humanos , Imageamento por Ressonância Magnética , Masculino , Nevo/complicações , Nevo/patologia , Neoplasias Cutâneas/complicações , Neoplasias Cutâneas/patologiaRESUMO
The Illegal Wildlife Trade (IWT) represents a multi-billion dollar black-market industry whereby wild species are illegally taken from their natural environment and sold. A common question asked by wildlife forensic scientists pertains to species and/or genus identity, which currently requires multi-step processing. Our work details the development of three HyBeacon® probes, used for the presumptive detection of rhinoceros, pangolin and key target species in the Panthera genus. The approach can be performed in a single tube using melt curve analysis and provide rapid assessment of sample identity. Using synthetic DNA of representative species, early data suggest the approach is sensitive enough to achieve species identification with <10â¯cells. Future development and assay validation can allow the rapid screening of multiple seized items before confirmatory DNA sequencing.