[Morphofunctional changes in the myocardium after extensive bilateral resection of the lungs]. / Morfofunktsional'nye izmeneniia miokarda posle dvustoronnei obshirnoi rezektsii legkikh.

In the experiment, performed on 89 dogs, after 67-75% resection of the lungs, functional morphology of the myocardium has been studied by means of histological, electron microscopical and morphometrical methods. Bilateral extensive resections of the lungs are accompanied with hypertrophy of the cardiac muscle, that is revealed at all the levels of its structural organization. Simultaneously, the hypertrophy develops against the background of dystrophic and destructive changes of the myocardium, their depth and extensiveness correlate with duration of the postoperative observations. If an extrapulmonary anastomosis is formed between the inferior lobular pulmonary artery and the corresponding vein before the resection of 67-75% of the lungs, it eliminates the acute overloading of the right ventricle, makes better conditions for development of compensatory-adaptive processes in the myocardium, prevents advancement of the cardio-pulmonary deficiency during the postoperative period.

[Structural and functional characteristics of myocardial capillaries after resection of the lungs]. / Strukturno-funktsional'nye osobennosti kapilliarov miokarda posle rezektsii legkikh.

In the experiment performed on 107 dogs, after resection of 33-75% of the pulmonary volume, it has been stated that considerable disturbances take place in the myocardial microcirculatory bed. At early stage after the operation the amount of capillaries per 1 mm2 of the section increases, their lumens become wide. With elapse of time after the operation, as a result of myocardial hypertrophy, density in arrangement of the capillaries decreases, and the transversal section area of the cardiomyocyte per one capillary increases. In the capillary walls destructive changes are also noted; they result in myocardiodistrophy and in development of cardiac failure.