[Method of determining methemoglobin in cadaver blood]. / O metodike opredeleniia metgemoglobina v trupnoi krovi.

Poisoning with methemoglobin toxins are not rare in forensic medical practice, but there is still no reliable method for measuring methemoglobin in cadaveric biological fluids and tissues. The author investigated factors affecting evaluation of natural amounts of methemoglobin in the blood, compared several methods for methemoglobin measurements, and developed qualitative characteristics indicating the presence of methemoglobin in cadaveric blood. A rational method for measuring methemoglobin in the blood, blood clots, and tissues is offered for forensic chemical and biochemical evaluations.

[The procedure for the wide use of praziquantel in a complex of measures to control opisthorchiasis. 2. The tolerance and efficacy of Russian-made azinox in mass treatment in foci]. / Taktika shirokogo primeneniia prazikvantelia v komplekse mer bor'by s opistorkhozom. Soobshchenie 2. Perenosimost' i éffektivnost' azinoksa otechestvennogo proizvodstva pri massovom lechenii v ochagakh.

Whether the Russian praziquantel analog azinox can be widely used in the foci of opisthorchiasis was first assessed. The outpatient treatment of 7405 patients with the agent in doses of 30, 40, 60 mg/kg body weight revealed that azinox tolerance did not depend upon the intensity and degree of clinical infection signs but it was slightly worse when a dose of 60 mg/kg was given. Children virtually showed no adverse reactions, in adults their frequency was no more than 52 +/- 1.4%. The parasitological efficiency of azinox in the used doses was 96-99% in children and 82-86% in adults. There was a clinical improvement in 65% of the treated. Thus, the national drug azinox is not inferior to the imported agent bilthricide in tolerance, parasitological and clinical efficiency. Bearing in mind the equal efficiency, but the better tolerance and less cost of the drug doses of 30 and 40 mg/kg body weight, it is advisable to use them in the foci for outpatient treatment.

[The procedure for the wide use of praziquantel in a complex of measures to control opisthorchiasis. 1. The tolerance and efficacy of different doses of biltricide during outpatient use in foci]. / Taktika shirokogo primeneniia prazikvantelia v komplekse mer bor'by s opistorkhozom. Soobshchenie 1. Perenosimost' i éffektivnost' razlichnykh doz biltritsida pri ambulatornom primenenii v ochagakh.

The results of wide uses of praziquantel (bilthricide, Bayer, Merck) to treat 2,440 persons in the outpatient setting of the endemic foci of opisthorchiasis in Tomsk Province suggest that the agent is highly effective (on the average of 97%) and well tolerable. There are no great differences in the efficiency of treatment, the frequency and magnitude of adverse reactions during out- and inpatient treatments. There are no either basic differences in the efficacy of praziquantel doses of 30, 40, and 60 mg used in the treatment of patients with Opisthorchis infection in whom 1 to 1.00 eggs per g feces are found. The use of praziquantel in a daily dose of 30 or 40 mg/kg in the outpatient setting permits the mass drug therapy of the population in the endemic foci, by reducing expenses on treatment. It is advisable to continue investigations of praziquantel used in small doses among the populations at low infection risk.

[The point-scale assessment of the intensity of the possible contamination by helminth eggs of large reservoirs in the Volga basin]. / Ball'naia otsenka intensivnosti vozmozhnogo zagriazneniia iaitsami gel'mintov krupnykh vodokhranilishch basseina Volgi.

Possibility for the contamination of man-made lakes by helminth eggs caused by superficial drain was estimated. The estimation allowed one to apply a differential approach to the organization of protection measures.

[The prognosis of the diphyllobothriasis situation in water reservoirs under construction (the Adyche and Sakhalin reservoirs)]. / Prognozirovanie situatsii po difillobotriozom na proektiruemykh vodokhranilishchakh (Adychanskoe i Sakhalinskoe).

The investigations conducted in the construction area of Adyche and Sakhalin water reservoirs made it possible to work out the prognosis for the changes in the situation on diphyllobothriasis. In the area of Adyche water reservoir the population invasion with D. latum is likely to increase, while in the area of Sakhalin water reservoir the situation on D. klebanovskii sp. no. will remain unchanged.

[The helminthiasis situation in areas of the influence of water storage basins on the territory of Cherkassy Province]. / Situatsiia po gel'mintozam v zonakh vliianiia vodokhranilishch na territorii Cherkasskoi oblasti.

The situation with helminthiases has been studied on the right tributaries of the Dnieper, the upper reaches of Kremenchug storage pond and in the storage ponds of the South Bug basin. The existence of genuine opisthorchiasis foci in Kremenchug storage pond is at present impossible due to the absence of Codiella mollusks. Fish of the carp family is infected in the right tributaries of the Dnieper. No diphyllobothriasis foci have been identified in the upper reaches of Kremenchug storage pond. Opisthorchiasis and diphyllobothriasis foci have not been identified in storage ponds of the South Bug basin and the formation of such foci in this area is not expected in the future. The population infectivity with geohelminthiases in these storage pond areas remained unchanged.

[Approaches to predicting the diphyllobothriasis and opisthorchiasis situation in connection with the reconstruction of the water supply economy in the USSR]. / Podkhody k prognozirovaniiu situatsii po difillobotriozu i opistorkhozu v sviazi s rekonstruktsiei vodnogo khoziaistva strany.

The effect of some physical-geographical and anthropogenic factors on the circulation of Diphyllobothriidae and Opisthorchis at the hydrotechnical objects of various regions of the USSR is analysed. It is emphasized that these factors affect primarily the first intermediate hosts of parasites. In opisthorchiasis changes in the intensity of the epidemic process may take place within the limits of mollusca distribution area. In diphyllobothriasis, the area of distribution may be expanded and new foci may be formed with the changes in the river hydroregimen.

[Status of the musculo-venous pump of the thigh in varicose veins]. / Sostoianie myshechno-venoznoi "pompy" bedra pri varikoznoi bolezni.

By means of the ultrasound flowmetry, phlebography, rheovasography and phlebotonometry, 51 patients with varicose disease was examined. It was established, that musculo-venous++ "pump" of a thigh played the leading part in the venous return. In stages I and II of varicose disease, the function of musculo-venous++ "pump" of a thigh was impaired moderately, its sharp disfunction was noted in stage III of the disease.

[The spread and evaluation of the potential for the formation of new foci of opisthorchiasis and diphyllobothriasis in the Yenisei basin]. / Rasprostranenie i otsenka vozmozhnostei formirovaniia novykh ochagov opistorkhoza i difillobotrioza v basseine Eniseia.

Current epidemiological situation on opisthorchiasis and bothriocephaliasis and possibility of its alteration due to hydro construction is characterized. Construction of the Bratsk and Krasnoyarsk reservoirs led to development of new large foci of bothriocephaliasis. There is a possibility of developing new foci near other operating reservoirs or near those under construction and design. Foci of bothriocephaliasis on the Yenisei reservoirs are supposed to be more intensive than foci on the Angara reservoirs. Some opisthorchiasis foci are found in the Biryusa basin, local cases of human invasion are registered in regions on the Taseyeva river, down the Angara, and in one of the Yenisei regions where invasion foci of low intensity are supposed to exist. Reservoir construction on the Yenisei and Angara will not promote the development of new opisthorchiasis foci.

[An evaluation using an information analysis method of the environmental factors affecting the diphyllobothriasis situation in water reservoirs]. / Otsenka metodom informatsionnogo analiza faktorov okruzhaiushchei sredy, vliiaiushchikh na situatsiiu po difillobotriozu na vodokhranilishchakh.

Information analysis was used to assess the influence of certain anthropogenic factors on the situation in water reservoirs of the Daugava, Dnieper, Don, Volga, Kama, Ob, Yenisei, Amu Darya and Zeya river basins with respect to diphyllobothriasis.

[Assessment of run-off in pollution of bodies of water with diphyllobothriiidae eggs by hydrometeorologic indicators]. / Otsenka po gidrometeorologicheskim pokazateliam znacheniia poverkhnostnykh stokov v zagriaznenii vodoemov iaitsami difillobotriid.

Use of some hydrometheorological characteristics for assessing quantitative parameters of surface run-off in water reservoirs' areas is suggested. Conclusions concerning the potential threat of anthropogenic water pollution are drawn on the basis of above-mentioned indicators.