RESUMO
A total of 95 women aged 47 to 72 were examined with a history of bloody discharge in the postmenopause. Sex hormones, hydrocortisone, thyroid hormones, blood lipids and serotonin, noradrenaline and adrenalin excretion were assessed. Histologic examinations of endometrial scrapings off were carried out in all the cases. A table for prediction of endometrial diseases has been created on the basis of the findings. Cancer development risk factors were singled out.
Assuntos
Neoplasias do Endométrio/epidemiologia , Endométrio/patologia , Lesões Pré-Cancerosas/epidemiologia , Hemorragia Uterina/epidemiologia , Idoso , Atrofia/complicações , Atrofia/epidemiologia , Neoplasias do Endométrio/etiologia , Feminino , Humanos , Pessoa de Meia-Idade , Pós-Menopausa , Lesões Pré-Cancerosas/etiologia , Pré-Menopausa , Prognóstico , Estudos Prospectivos , Fatores de Risco , Hemorragia Uterina/complicaçõesRESUMO
Radioimmunoassay was used for the assessment of serum hormone levels. Dysfunctions in the fetoplacental system (decreased levels of progesterone and estrogens) were revealed as were elevated levels of somatotropic hormone, which were in inverse proportion to the fetal weight, in 20 pregnant females who abused alcohol during the entire pregnancy. It was suggested that higher production of somatotropic hormone could occur in the presence of hypophyseal tension which had been evidently developed before the pregnancy.