[Clinical-laboratory study of the efficacy of combined drug Cifran CT in complex therapy of inflammatory periodontal disease].

Data on clinical and microbiological study on 40 patients showed sufficient efficacy of combined preparation Cifran CT used in combined therapy of inflammatory periodontal disease.

[The analgesic action of the preparation Ketanov in the combined treatment of patients with pulpitis and periodontitis]. / Anal'geticheskoe deistvie preparata Ketanov v kompleksnom lechenii bol'nykh s pul'pitami i periodontitami.

The purpose of this clinical investigation was to compare analgetic effect of analgin and Ketanov on posttreatment pain after canal filling in 50 patients with pulpitis and periodontitis. Clinical data have shown Ketanov effectiveness, absence of side effects. Marked reduction of pain was shown in all patients getting Ketanov, no analgetic effect was revealed in 20% patients getting analgin.

[Toxicological study of the Soviet tetracyclic antidepressant inkazan]. / Toksikologicheskoe izuchenie otechestvennogo tetratsiklicheskogo antidepressanta inkazana.

The toxicology of an original Soviet antidepressant inkasan-3-methyl-8-methoxy-3H, 1,2,5,6-tetrahydropyrazino [1,2,3-ab] beta-carboline hydrochloride was studied in different types of experimental animals (mice, rats, rabbits, dogs). It was established that the drug is less toxic than imipramine. The toxic manifestations (seizures, stereotypy) seen in dogs receiving high doses of inkasan for a long time are likely to be linked with a stimulating component that characterizes the drug action on the central nervous system.

[Toxicological characteristics of the Soviet antidepressant pyrazidol]. / Toksikologicheskaia kharakteristika otechestvennogo antidepressanta pirazidola.

It has been demonstrated in different species of experimental animals (mice, rats, cats, dogs) that the Soviet drug pyrazidol is a little toxic drug. Prolonged repeated administration of pyrazidol does not exert any damaging action on the vitally important organs and systems of the body. Pyrazidol is less toxic than imipramine.