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1.
Nature ; 525(7567): 33, 2015 Sep 03.
Artigo em Inglês | MEDLINE | ID: mdl-26333458
2.
Phys Rev Lett ; 115(8): 081101, 2015 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-26340176

RESUMO

We present a search for γ-ray emission from the direction of the newly discovered dwarf galaxy Reticulum II. Using Fermi-LAT Collaboration data, we detect a signal that exceeds expected backgrounds between ∼2-10 GeV and is consistent with annihilation of dark matter for particle masses less than a few ×10^{2} GeV. Modeling the background as a Poisson process based on Fermi-LAT diffuse models, and taking into account trial factors, we detect emission with p value less than 9.8×10^{-5} (>3.7σ). An alternative, model-independent treatment of the background reduces the significance, raising the p value to 9.7×10^{-3} (2.3σ). Even in this case, however, Reticulum II has the most significant γ-ray signal of any known dwarf galaxy. If Reticulum II has a dark-matter halo that is similar to those inferred for other nearby dwarfs, the signal is consistent with the s-wave relic abundance cross section for annihilation.

3.
Phys Rev Lett ; 107(24): 241303, 2011 Dec 09.
Artigo em Inglês | MEDLINE | ID: mdl-22242988

RESUMO

Dwarf spheroidal galaxies are known to be excellent targets for the detection of annihilating dark matter. We present new limits on the annihilation cross section of weakly interacting massive particles based on the joint analysis of seven Milky Way dwarfs using a frequentist Neyman construction and Pass 7 data from the Fermi Gamma-Ray Space Telescope. We exclude generic weakly interacting massive particle candidates annihilating into bb with a mass less than 40 GeV that reproduce the observed relic abundance. To within 95% systematic errors on the dark matter distribution within the dwarfs, the mass lower limit can be as low as 19 GeV or as high as 240 GeV. For annihilation into τ+ τ-, these limits become 19, 13, and 80 GeV, respectively.

4.
Science ; 305(5692): 1966-8, 2004 Sep 24.
Artigo em Inglês | MEDLINE | ID: mdl-15448271

RESUMO

We present the genomic sequence of Legionella pneumophila, the bacterial agent of Legionnaires' disease, a potentially fatal pneumonia acquired from aerosolized contaminated fresh water. The genome includes a 45-kilobase pair element that can exist in chromosomal and episomal forms, selective expansions of important gene families, genes for unexpected metabolic pathways, and previously unknown candidate virulence determinants. We highlight the genes that may account for Legionella's ability to survive in protozoa, mammalian macrophages, and inhospitable environmental niches and that may define new therapeutic targets.


Assuntos
Genoma Bacteriano , Legionella pneumophila/genética , DNA Bacteriano , Transferência Genética Horizontal , Legionella pneumophila/patogenicidade , Legionella pneumophila/fisiologia , Plasmídeos
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