Type 2 autoimmune pancreatitis associated with severe ulcerative colitis: Three case reports.

BACKGROUND: Type two autoimmune pancreatitis is a rare and difficult to diagnose, steroid responsive non-IgG4 inflammatory pancreatopathy that can be associated with inflammatory bowel disease. CASE SUMMARY: This case series describes three cases with varied clinical presentations and re-presentations of autoimmune pancreatitis, and all associated with an aggressive course of ulcerative colitis. The pancreatopathy was independent of bowel disease activity and developed in one case following colectomy. CONCLUSION: Clinician awareness about this condition is important to allow early diagnosis, treatment and avoid unnecessary pancreatic surgery.