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Mol Cell ; 27(2): 311-323, 2007 07 20.
Artigo em Inglês | MEDLINE | ID: mdl-17643379

RESUMO

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the editors. Molecular Cell has retracted this article following the results of an investigation carried out by Leiden University Medical Center's Committee of Scientific Integrity, which concluded that unacceptable data manipulation by the last author Maria Fousteri led to breaches of scientific integrity, making these results unreliable. Section 2.2, item 2 of the report indicates several duplications in Figure 4 and that, upon inspection of original data, several proteins stained for by western blotting following immunoprecipitation were incorrectly assigned (Figure 4B). The XPA panel in Figure 4A is a mirrored duplication of an image that was published in Figure 5C of Fousteri et al., 2006 (Mol. Cell 23, 471-482, https://doi.org/10.1016/j.molcel.2006.06.029). Additional details can be found in the redacted version of the investigation report (https://www.lumc.nl/cen/att/80813053317221/1263833/report-lumc-committee-scientific-integrity).


Assuntos
Quebras de DNA de Cadeia Simples , DNA Ligases/metabolismo , Reparo do DNA/fisiologia , Proteínas de Ligação a DNA/metabolismo , Ciclo Celular , Células Cultivadas , DNA Ligase Dependente de ATP , DNA Ligases/química , DNA Polimerase II/química , DNA Polimerase II/metabolismo , DNA Polimerase III/química , DNA Polimerase III/metabolismo , Proteínas de Ligação a DNA/química , Regulação para Baixo , Humanos , Modelos Biológicos , Complexos Multiproteicos , Fotobiologia , Proteínas de Ligação a Poli-ADP-Ribose , Raios Ultravioleta/efeitos adversos , Proteína 1 Complementadora Cruzada de Reparo de Raio-X , Proteínas de Xenopus
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