True ectopic ovary in the right iliac fossa mimicking acute appendicitis and associated with ipsilateral renal agenesis.

Ectopic ovarian tissue is a rare gynecologic condition. The presence of ectopic ovary may be accompanied by maldevelopments of the genital and urinary tract. We report an extremely rare case of a 39-year-old woman presenting with abdominal pain localized in the right lower quadrant. During the preoperative investigation and the exploratory laparotomy, an ectopic ovary in contact with the appendix accompanied by a single left kidney was found. The present report also includes a review of the related published work. To the best of our knowledge, this is one of the very few cases reported describing the co-occurrence of true ovarian ectopia and ipsilateral renal agenesis.

Primary hepatic carcinoid; a diagnostic dilemma: a case report.

INTRODUCTION: Primary hepatic carcinoid tumours (PHCTs) are extremely rare neuroendocrine neoplasms. Only 58 cases have been reported in the literature and less than 10 cases were functional. CASE PRESENTATION: We present a case of a 65 years old, Caucasian female with a large unresectable primary hepatic carcinoid tumor secreting 5-hydroxyindoleacetic acid (5-HIAA), presented with flushing and diarrhoea and treated with trans-catheter arterial embolization (TACE) and subsequent administration of lanreotide (long acting somatostatin analogue). CONCLUSION: The diagnosis of PHCTs is difficult due to their common radiologic characteristics with other liver lesions. Their diagnosis is based on the exclusion of other sites of disease and the histologic confirmation. Although the mainstay of treatment when is technically feasible is surgical resection with optimal 5-year survival and low recurrence rate, in cases of unresectable disease palliation with combination of TACE and administration of somatostatin analogues have good results in controlling the disease and the patients symptoms.

Focal lymphoplasmacytic sclerosing pancreatitis: radiological-pathological correlation.

OBJECTIVE: To correlate cross-sectional imaging findings with histological results in patients with histopathologically proven lymphoplasmacytic sclerosing pancreatitis (LSP) after surgery. METHODS: Four cases of resectable pancreatic lesions that were proven to represent LSP are presented in our study. All patients were thought to harbor malignancy. A detailed research in patients' records was retrospectively done concerning clinical presentation and imaging studies. RESULTS: Characteristic imaging findings consistent with fibrotic changes were evident in only one case on magnetic resonance imaging. A discrete mass was evident on imaging in 2 patients that correlated well with pathology results. In the other patients, the extent of inflammatory changes on microscopic examination correlated well with the degree of pancreatic head enlargement on imaging studies. CONCLUSIONS: Lymphoplasmacytic sclerosing pancreatitis is a particular form of benign inflammatory pancreatic disease that is extremely difficult to diagnose preoperatively. Familiarization with the variable imaging findings is essential and may result in the reduction of the number of patients with LSP who undergo surgical resection.

Beneficial effect of an antibody against interleukin-2 receptor (daclizumab) in an experimental model of hepatocyte xenotransplantation.

AIM: To investigate the use of Daclizumab (Dmab) as an immunosuppressive agent in an experimental model of hepatocyte xenotransplantation (XenoTx) in rats with fulminant hepatic failure (FHF). METHODS: Two white male New Zealand rabbits were used as donors and 68 Wistar rats as recipients. FHF was induced by intravenous application of dimethylnitrosamine (DMNA). The isolated hepatocytes of the rabbits were xenotransplanted into the spleen of the rats 24 h after FHF induction. Group A (n = 13): no treatment; Group B (n = 14): FHF and XenoTx; Group C (n = 14): FHF and XenoTx and cyclosporin (CsA); Group D (n = 14): FHF and XenoTx and Dmab; Group E (n = 13): FHF and XenoTx and CsA and Dmab. The rats were followed for 15 d. RESULTS: Statistical analysis showed better survival among groups D (92.86%) and E (76.92%) compared to group A (all rats died after 72 h), group B (28.57%) or group C (71.43%), although the differences were not statistically significant. Biochemical evaluation of the liver enzymes and histology confirmed satisfactory function and engraftment, respectively. CONCLUSION: This experimental model has shown the safe, effective and beneficial use of Dmab in a xenotransplantation model of rabbit hepatocytes in rats.