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Ann Otol Rhinol Laryngol ; 128(4): 277-285, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30547680

RESUMO

OBJECTIVES:: The aim of this study was to assess the feasibility of the submucosal infusion combined with microflap dissection via laser CO2 as both a diagnostic and therapeutic procedure for superficial glottic lesions. To define a safe surgical procedure in terms of local control, a morphometric study of surgical margins was performed. METHODS:: From January 2011 to January 2016, we treated 122 patients with early glottic lesions with phonomicrosurgery. Patients with effective hydrodissection underwent a microflap and type I-II diagnostic cordectomy. In the others, a biopsy was carried out, and in the case of a malignant lesion, a type III to VI cordectomy was performed. Disease-free survival (DFS) for all the lesions was also determined according to comparative assessments of surgical margins. The Voice Handicap Index was used to evaluate functional outcomes. RESULTS:: In 27 cases (32%), hydrodissection was effective; specifically, 24 (88.8%) were premalignant lesions, and 3 (11.2%) had a carcinoma. In 56 patients (68%), hydrodissection was not adequate, and a biopsy was performed: 9 (16%) were premalignant and 47 (84%) malignant lesions. The DFS analysis suggests that margins >0.7 mm resulted in a cutoff that can guarantee a safe procedure in the case of effective hydrodissection ( P < .05). CONCLUSION:: Phonomicrosurgery may be both a diagnostic and therapeutic option with oncological efficacy for superficial glottic lesions of undetermined nature when surgical margins exceed 0.7 mm. In case of inadequate hydrodissection, the hypothesis of an infiltrative carcinoma warrants a wider cordectomy.


Assuntos
Carcinoma , Ressecção Endoscópica de Mucosa , Glote , Neoplasias Laríngeas , Laringectomia , Complicações Pós-Operatórias , Lesões Pré-Cancerosas , Adulto , Idoso , Idoso de 80 Anos ou mais , Biópsia , Carcinoma/diagnóstico , Carcinoma/patologia , Carcinoma/cirurgia , Intervalo Livre de Doença , Ressecção Endoscópica de Mucosa/efeitos adversos , Ressecção Endoscópica de Mucosa/métodos , Feminino , Retalhos de Tecido Biológico , Glote/diagnóstico por imagem , Glote/patologia , Glote/cirurgia , Humanos , Itália , Neoplasias Laríngeas/diagnóstico , Neoplasias Laríngeas/patologia , Neoplasias Laríngeas/cirurgia , Laringectomia/efeitos adversos , Laringectomia/instrumentação , Laringectomia/métodos , Lasers de Gás/uso terapêutico , Masculino , Margens de Excisão , Pessoa de Meia-Idade , Seleção de Pacientes , Complicações Pós-Operatórias/diagnóstico , Complicações Pós-Operatórias/fisiopatologia , Lesões Pré-Cancerosas/diagnóstico , Lesões Pré-Cancerosas/patologia , Lesões Pré-Cancerosas/cirurgia , Estudos Retrospectivos , Prega Vocal/patologia , Prega Vocal/cirurgia , Qualidade da Voz
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