RESUMO
Horizontal sound localization and syllable recognition skills were examined in a group of children with unilateral sensorineural hearing loss and a matched group of normal hearers. The results showed that the unilaterally hearing-impaired children performed more poorly than the normal counterparts in both localization and speech recognition of nonsense syllables. The unilaterally hearing-impaired children had considerable difficulty understanding in a background of noise. The clinical implications of these findings are discussed.
Assuntos
Percepção Auditiva , Perda Auditiva Neurossensorial/psicologia , Localização de Som , Percepção da Fala , Logro , Adolescente , Adulto , Percepção Auditiva/fisiologia , Limiar Auditivo/fisiologia , Criança , Feminino , Lateralidade Funcional , Humanos , Masculino , Fonética , Localização de Som/fisiologia , Percepção da Fala/fisiologiaRESUMO
A microfluorimetric technique has been used to analyze fluorescence in specimens of Schistosoma mansoni labeled with a dansylated analog of acetylcholine. Anticholinergic drugs inhibit the fluorescent labeling of living specimens. The effectiveness of anticholinergic agents can be expressed as a fractional decrease in observed fluorescence of specimens, and several drugs have been compared in this context. Atropine, eserine, carbachol and mecamylamine block fluorescence only at high concentrations (10(-4)--10(-3) M) while trifluoperazine and hycanthone block strongly at lower concentrations (10(-5) M). The findings reported here suggest that the relative activity of anticholinergic drugs is different in schistosomes and vertebrates.
