RESUMO
Chronic pneumonia was modelled on rabbits after Zakharyevskaya-Anichkov method in authors own modification. The treatment was performed in the karst cave. Unlike to control animals normalization of present alterations in left ventricle myocardium was observed in experimental rabbits, regimen and duration of stay in the cave being of great importance, e. g. animals kept in the cave uninterruptedly for 22 d displayed almost complete normalization of both myocardium with its vessels and a series of immunological and biochemical parameters.
Assuntos
Clima , Pneumonia/fisiopatologia , Doença Cardiopulmonar/etiologia , Animais , Masculino , Microscopia Eletrônica , CoelhosRESUMO
Under study were changes of intraorganic blood vessels of the heart and lungs in some experimental defects (open arterial defect, coarctation of the aorta, simultaneous existence of these two defects, stenosis of the pulmonary trunk, defect of the interatrial septum, triad of Fallot, syndrom of Lutembachet). Morphological data correlated with blood pressure in the pulmonary circulation and cardiac chambers. The complex of compensatory-adaptational mechanisms consisting of comparatively active and passive zones is formed in the heart and lungs. In most cases the changes develop in the vessels already existing. In hypertrophy of the myocardium when there is hypertension and hypervolemia in coronary vessels, sinusoids perform the function of blood reservoir, to a certain degree balancing the blood pressure, and luminar ducts relieve the muscle from excessive blood. The changes in the vascular system of the lung are directly dependent upon the pressure in the pulmonary circulation and the duration of observation. The closing arteries are the most active link in the chain of compensatory-adaptational mechanisms.