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J Infect Dis ; 200(12): 1901-6, 2009 Dec 15.
Artigo em Inglês | MEDLINE | ID: mdl-19919304

RESUMO

The distribution of the neurotropic alphaherpesviruses-herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) and varicella zoster virus (VZV)-was determined in autonomic and sensory ganglia of the head and neck obtained from formalin-fixed human cadavers. HSV-1 and VZV DNA were found in 18 of 58 and 16 of 58 trigeminal, 23 of 58 and 11 of 58 pterygopalatine, 25 of 60 and 14 of 60 ciliary, 25 of 48 and 11 of 48 geniculate, 15 of 50 and 8 of 50 otic, 14 of 47 and 4 of 47 submandibular, 18 of 58 and 10 of 58 superior cervical, and 12 of 36 and 1 of 36 nodose ganglia, respectively. HSV-2 was not detected at any site. Viral DNA positivity and location were independently distributed among autonomic and sensory ganglia of the human head and neck.


Assuntos
Gânglios/virologia , Cabeça/virologia , Herpesvirus Humano 1/isolamento & purificação , Herpesvirus Humano 3/isolamento & purificação , Pescoço/virologia , Idoso , Idoso de 80 Anos ou mais , DNA Viral/isolamento & purificação , Feminino , Herpesvirus Humano 2/isolamento & purificação , Humanos , Masculino
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