1.
Gene
; 74(1): 229-32, 1988 Dec 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3074011
2.
Bioorg Khim
; 11(11): 1572-3, 1985 Nov.
Artigo
em Russo
| MEDLINE
| ID: mdl-3004510
RESUMO
The recognition sequence and cleavage point of restriction endonuclease Eco781 have been determined as 5'-GGCGCC-. There are several known enzymes recognizing the same sequence, although the prototype NarI and isoschizomers NdaI and NunII cleave the substrate to produce 5'-protruding ends, whereas cleavage with isoschizomer BbeI results in 3'-protruding ends. Therefore, restrictase Eco78I, generating flush ends, may be regarded as an enzyme with new specificity among the restriction endonucleases recognizing the 5'-GGCGCC-sequence.