RESUMO
Although most infantile haemangiomas do not require treatment due to a natural history of spontaneous involution, some require early intervention. The Australasian Vascular Anomalies Network and the Australasian Paediatric Dermatology Network have developed a consensus statement for the treatment of infantile haemangiomas with oral propranolol. Infants with haemangiomas that are life threatening, at risk of ulceration, or at risk of causing a significant functional impairment, psychological impact or physical deformity should be treated early with oral propranolol. Oral propranolol is safe and effective and in most healthy infants oral propranolol can be started in an outpatient setting.
Assuntos
Consenso , Hemangioma Capilar/tratamento farmacológico , Síndromes Neoplásicas Hereditárias/tratamento farmacológico , Propranolol/uso terapêutico , Vasodilatadores/uso terapêutico , Monitoramento de Medicamentos , Humanos , Seleção de Pacientes , Propranolol/administração & dosagem , Vasodilatadores/administração & dosagemRESUMO
We describe an unusual case of multidrug-resistant miliary tuberculosis diagnosed 9 months after the commencement of infliximab treatment for psoriasis despite negative pretreatment tuberculosis screening, including chest X-ray and interferon-gamma release assay. After 4 months' treatment with amikacin, ethambutol, pyrazinamide and moxifloxacin, infliximab was restarted with concomitant anti-TB medications. No recurrence of tuberculosis has been detected 12 months after recommencing infliximab.
Assuntos
Anti-Inflamatórios não Esteroides/efeitos adversos , Anticorpos Monoclonais/efeitos adversos , Tuberculose Latente/diagnóstico , Tuberculose Miliar/etiologia , Tuberculose Resistente a Múltiplos Medicamentos/etiologia , Tuberculose Pulmonar/etiologia , Antituberculosos/uso terapêutico , Artrite Psoriásica/tratamento farmacológico , Reações Falso-Negativas , Humanos , Infliximab , Testes de Liberação de Interferon-gama , Tuberculose Latente/complicações , Masculino , Pessoa de Meia-Idade , Tuberculose Miliar/tratamento farmacológico , Tuberculose Resistente a Múltiplos Medicamentos/tratamento farmacológico , Tuberculose Pulmonar/tratamento farmacológicoRESUMO
We describe the development of psoriatic nail disease due to metoprolol in a 58-year-old woman who was being treated for cardiac arrhythmias. The nail condition was unresponsive to topical and systemic treatments but resolved completely with the withdrawal of metoprolol. The reaction recurred with drug rechallenge and resolved when the drug was ceased.
Assuntos
Antiarrítmicos/efeitos adversos , Metoprolol/efeitos adversos , Doenças da Unha/induzido quimicamente , Psoríase/induzido quimicamente , Feminino , Humanos , Pessoa de Meia-Idade , Taquicardia Supraventricular/tratamento farmacológicoRESUMO
Cutaneous endometriosis that arises de novo, without a prior history of surgery, is a rare phenomenon. The clinical diagnosis of cutaneous endometriosis remains challenging due to the variable clinical appearance and symptoms of the condition, and therefore must be considered in the differential diagnosis of any umbilical lesion. We report a 31-year-old woman who presented with spontaneous cutaneous endometriosis of the umbilicus.
