RESUMO
PURPOSE/METHODS: To report a rare case of a tumor in a conjunctival location, a giant cell collagenoma. Tissue was stained with hematoxylin-eosin, periodic acid-Schiff, and Masson's trichromic stain and studied by immunohistochemistry. RESULTS/CONCLUSION: The clinical and histopathologic features of conjunctival giant cell collagenoma are similar to characteristics of the same tumor occurring in other parts of the body. This is the first report of this tumor in the eye.
Assuntos
Neoplasias da Túnica Conjuntiva/patologia , Tumores de Células Gigantes/patologia , Antígenos CD/análise , Antígenos de Diferenciação Mielomonocítica/análise , Colágeno/análise , Neoplasias da Túnica Conjuntiva/química , Neoplasias da Túnica Conjuntiva/diagnóstico , Diagnóstico Diferencial , Tumores de Células Gigantes/química , Tumores de Células Gigantes/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Proteínas de Neoplasias/análise , Vimentina/análiseRESUMO
We report a case of endogenous nocardial endophthalmitis in a 32-year-old man with systemic lupus erythematosus. The patient developed pulmonary and ocular disease while on systemic corticosteroid and cyclophosphamide treatment. The intraocular infection progressed to a scleral fistula, and was treated with pars plana vitrectomy, lensectomy, intravitreous and intravenous antibacterial therapy. The diagnosis of Nocardia asteroides was made by isolation and growth of colonies from samples of a vitreous specimen and bronchioloalveolar aspirates. The eye became phthisical, it was eviscerated, and histopathogical examination was carried out.
Se describe un caso de endoftalmitis endógena por nocardia en un varón de 32 años con diagnóstico de lupus eritematoso sistémico. El paciente desarrolló compromiso pulmonar y ocular luego de meses de tratamiento con corticoides y ciclofosfamida. La infección intraocular, de rápida evolución a fístula escleral, recibió tratamiento con vitrectomía, lensectomía y terapia antibacteriana intravítrea y endovenosa. Se aislaroncolonias de Nocardia asteroides a partir de material vítreo y aspirado bronquioloalveolar. El ojo afectado evolucionó a ptisis bulbi y fue posteriormente eviscerado, y se realizó el estudio histopatológico.
Assuntos
Adulto , Humanos , Masculino , Endoftalmite/microbiologia , Lúpus Eritematoso Sistêmico/complicações , Nocardia asteroides , Nocardiose , Endoftalmite/terapia , Nocardiose/terapia , VitrectomiaRESUMO
We report a case of endogenous nocardial endophthalmitis in a 32-year-old man with systemic lupus erythematosus. The patient developed pulmonary and ocular disease while on systemic corticosteroid and cyclophosphamide treatment. The intraocular infection progressed to a scleral fistula, and was treated with pars plana vitrectomy, lensectomy, intravitreous and intravenous antibacterial therapy. The diagnosis of Nocardia asteroides was made by isolation and growth of colonies from samples of a vitreous specimen and bronchioloalveolar aspirates. The eye became phthisical, it was eviscerated, and histopathogical examination was carried out.(AU)
Se describe un caso de endoftalmitis endógena por nocardia en un varón de 32 años con diagnóstico de lupus eritematoso sistémico. El paciente desarrolló compromiso pulmonar y ocular luego de meses de tratamiento con corticoides y ciclofosfamida. La infección intraocular, de rápida evolución a fístula escleral, recibió tratamiento con vitrectomía, lensectomía y terapia antibacteriana intravítrea y endovenosa. Se aislaroncolonias de Nocardia asteroides a partir de material vítreo y aspirado bronquioloalveolar. El ojo afectado evolucionó a ptisis bulbi y fue posteriormente eviscerado, y se realizó el estudio histopatológico.(AU)
Assuntos
Adulto , Humanos , Masculino , Endoftalmite/microbiologia , Lúpus Eritematoso Sistêmico/complicações , Nocardiose , Nocardia asteroides , Endoftalmite/terapia , Nocardiose/terapia , VitrectomiaRESUMO
PURPOSE/METHODS: To report the pathological findings in a case of intravitreous cilia with macular pucker. We considered clinical factors to establish treatment. A pars plana vitrectomy and premacular membrane peeling were performed. Surgical samples were removed and studied with PAS, hematoxylin-eosin, Masson's Trichromic and immunohistochemistry. RESULTS/CONCLUSION: The histopathological examination disclosed the presence of cilia partially surrounded by a cuticle layer and internal limiting membrane with a celullarity increase. Surgical extraction is indicated in those cases in which the intraocular cilia are associated with any surgically treatable process or when it produces ocular inflammation or visual disturbance.
