1.
Immunopharmacology
; 43(2-3): 145-7, 1999 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10596846
RESUMO
An increase of bradykinin (BK) plasma levels together with the activation coagulation cascade, fibrinolysis, complement and cytokines was observed during cardiopulmonary bypass (CPB). Since the procedure of extracorporeal circulation completely excludes the lung, the major site of BK catabolism, our data suggest that a reduced catabolism could contribute to the increase of BK during CPB.